Keywords
How to Cite
Abstract
There is evidence of the importance of circulating tumor cells in bloodstream as a factor of poor prognosis of cancer. The optimum method for isolating and studying of these cells is not defined. The most common methods are either based on the isolation of tumor genetic material from blood or on immune-mediated isolation of epithelial tumor cells. The first group of methods is characterized by a lack of specificity, while the latter do not allow identifying a pool of cells undergone in bloodstream epithelial-mesenchymal transformation. There is presented an overview of results of clinical trials of a new technique of isolation of tumor cells from bloodstream based on the patients’ blood filtration through a membrane with defined pore sizes (ISET-Isolation by SizE of Tumor cells).References
Злокачественные новообразования в России в 2010 году (заболеваемость и смертность). Под ред. В.И. Чиссова, В.В. Старинского, Г.В. Петровой. М.: ФГБУ «МНИОИ им. П.А. Герцена» Минздравсоцразвития России. - 2012. - 260 с.
Патютко Ю.И., Сагайдак И.В., Тупицын Н.Н. и др. Влияние циркуляции опухолевых клеток в крови на прогноз при операциях на печени по поводу злокачественных опухолей // Хирургия. - 2011. - № 4. - С. 22-26.
Cohen S.J., Punt C.J., lannotti N. и др. Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer // J Clin Oncol. - 2008. - Vol. 26. - № 19. - P. 3213-3221.
Cristofanilli M., Budd G.T., Ellis M.J. и др. Circulating tumor cells, disease progression, and survival in metastatic breast cancer // N Engl J Med. - 2004. - Vol. 351. - № 8. - P. 781-791.
De Bono J.S., Scher H.I., Montgomery R.B. и др. Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer // Clin Cancer Res. - 2008. - Vol. 14. - P. 6302-6309.
De Giorgi V., Pinzani P., Salvianti F. и др. Application of a filtration- and isolation-by-size technique for the detection of circulating tumor cells in cutaneous melanoma // J Invest Dermatol. - 2010. - Vol. 130. - № 10. - P. 2440-2447.
Farace F., Massard C., Vimond N. и др. A direct comparison of CellSearch and ISET for circulating tumour-cell detection in patients with metastatic carcinomas // Br J Cancer. - 2011. - Vol. 105. - N 6. - P. 847-53.
Fehm T., Solomayer E.F., Meng S. и др. Methods for isolating circulating epithelial cells and criteria for their classification as carcinoma cells // Cytotherapy. - 2005. - Vol. 7. - N 2. - P. 171-185.
Franken B., de Groot M.R., Mastboom W.J. и др. Circulating tumor cells, disease recurrence and survival in newly diagnosed breast cancer // Breast Cancer Res. - 2012. - Vol. 14. - № 5. - P. R133.
Friedlander T.W., Premasekharan G., Paris P.L. Looking back, to the future of circulating tumor cells // Pharmacol Ther. - 2014. - Vol. 142. - № 3. - P. 271-280.
Hofman V.J., Ilie M.I., Bonnetaud C. и др. Cytopathologic detection of circulating tumor cells using the isolation by size of epithelial tumor cell method // Am J Clin Pathol. - 2011. - Vol. 135. - P. 146-156.
Hofman V., Long E., Ilie M. и др. Morphological analysis of circulating tumour cells in patients undergoing surgery for non-small cell lung carcinoma using the isolation by size of epithelial tumour cell (ISET) method // Cytopathology. - 2012. - Vol. 23. - № 1. - P. 30-38.
Hofman V., Ilie M., Long-Mira E. и др. Usefulness of immunocytochemistry for the detection of the BRAFV600E mutation in circulating tumor cells from metastatic melanoma patients // J Invest Dermatol. - 2013. - Vol. 133. - N10. - P. 1378-1381.
Ilie M., Long E., Butori C. и др. ALK-gene rearrangement: a comparative analysis on circulating tumour cells and tumour tissue from patients with lung adenocarcinoma // Ann Oncol. - 2012. - Vol. 23. - № 11. - P. 2907-2913.
Khoja L., Backen A., Sloane R. и др. A pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker // Br J Cancer. - 2012. - Vol. 106. - № 3. - P. 508-516.
Khoja L., Shenjere P., Hodgson C. и др. Prevalence and heterogeneity of circulating tumour cells in metastatic cutaneous melanoma // Melanoma Res. - 2014. - Vol. 24. - № 1. - P. 40-46.
Krebs M.G., Hou J.M., Sloane R. и др. Analysis of circulating tumor cells in patients with non-small cell lung cancer using epithelial marker-dependent and -independent approaches // J Thorac Oncol. - 2012. - Vol. 7. - № 2. - P. 306-315.
Mazzini C., Pinzani P., Salvianti F. и др. Circulating tumor cells detection and counting in uveal melanomas by a filtration-based method // Cancers (Basel). - 2014. - Vol. 6. - № 1. - P. 323-332.
Paterlini-Brechot P., Benali N.L. Circulating tumor cells (CTC) detection: Clinical impact and future directions // Cancer Letters. - 2007. - Vol. 253. - P. 180-204.
Pinzani P., Salvadori B., Simi L. и др. Isolation by size of epithelial tumor cells in peripheral blood of patients with breast cancer: correlation with real-time reverse transcriptase-polymerase chain reaction results and feasibility of molecular analysis by laser microdissection // Hum Pathol. - 2006. - Vol. 37. - № 6. - P. 711-718.
Riethdorf S., Muller V., Zhang L. и др. Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial // Clin Cancer Res. - 2010. - Vol. 16. - № 9. - P. 2634-2645.
Siegel R., Naishadham D., Jemal A. Cancer Statistics, 2013 // CA CANCER J CLIN. - 2013. - Vol. 63. - P. 11-30.
Vona G., Sabile A., Louha M. и др. Isolation by size of epithelial tumor cells: a new method for the immunomorphological and molecular characterization of circulating tumor cells // Am J Pathol. - 2000. - Vol. 156. - P. 57-63.
Vona G., Estepa L., Bèoud C. и др. Impact of cytomorphological detection of circulating tumor cells in patients with liver cancer // Hepatology. - 2004. - Vol. 39. - № 3. - P. 792-797.
All the Copyright statements for authors are present in the standart Publishing Agreement (Public Offer) to Publish an Article in an Academic Periodical 'Problems in oncology' ...