Korotkevich, P. E., Pivovarchik , S. N., Gulenko , O. V., Saridze , E. K., Shumovets , V. V., & Androlojt , I. E. (2025). Case Report of Surgical Treatment of an Active Left Atrial Paraganglioma. Voprosy Onkologii, 71(1), OF–2019. https://doi.org/10.37469/0507-3758-2025-71-1-OF-2019

Abstract

Introduction. Paragangliomas are rare neuroendocrine tumors that arise from extra‐adrenal parasympathetic or sympathetic ganglia neural crest cells. Cardiac paragangliomas are exceedingly rare tumors.

Case description. A case report of surgical treatment of an active left atrial paraganglioma is described. A combined approach was used. Left-sided VATS with tumour mobilization combined with right-sided thoracotomy with cardiopulmonary bypass was performed.

Conclusion. Left-sided VATS with tumor mobilization combined with right-sided thoracotomy for removal of the left atrial tumor with its plastic surgery allows, in our opinion, safe isolation of the tumor. Connecting a heart-lung machine from a right-sided thoracotomy is technically straightforward.

https://doi.org/10.37469/0507-3758-2025-71-1-OF-2019

##article.numberofdownloads## 17

##article.numberofviews## 58

pdf (Русский)

References

WHO Classification of Tumors. Thoracic tumors. WHO classification of tumors editorial board. 5th ed. Vol.5. France, Lyon: IARC. 2021. ISBN-13; 978-92-832-4506-3.

Hayek E.R., Hughes M.M., Speakman E.D., et al. Cardiac paraganglioma presenting with acute myocardial infarction and stroke. Ann Thorac Surg. 2007; 83(5): 1882-1884.-DOI: https://doi.org/10.1016/j.athoracsur.2006.12.023.

Joynt K.E., Moslehi J.J., Baughman K.L. Paragangliomas: etiology, presentation, and management. Cardiol Rev. 2009; 17(4): 159-164.-DOI: https://doi.org/10.1097/CRD.0b013e3181a6de40.

Alakeel F., Al Sannaa G., Ibarra-Cortez S.H., et al. Cardiac paragangliomas: A case series with clinicopathologic features and succinate dehydrogenase B immunostaining. Ann Diagn Pathol. 2020; 45: 151477.-DOI: https://doi.org/10.1016/j.anndiagpath.2020.151477.

Guenthart B.A., Trope W., Keeyapaj W., et al. Intracardiac paragangliomas: surgical approach and perioperative management. Gen Thorac Cardiovasc Surg. 2021; 69(3): 555-559.-DOI: https://doi.org/10.1007/s11748-020-01503-2.

Chan E.Y., Ali A., Umana J.P., et al. Management of primary cardiac paraganglioma. J Thorac Cardiovasc Surg. 2022; 164(1): 158-166.-DOI: https://doi.org/10.1016/j.jtcvs.2020.09.100.

Yamamoto Y., Kodama K., Yamato H., Takeda M. Successful removal of giant intrapericardial paraganglioma via posterolateral thoracotomy. Case Rep Surg. 2014; 2014: 308462.-DOI: https://doi.org/10.1155/2014/308462.

Marthy A.G., Smith N., Samy S., et al. Robotic approach to a subcarinal functional paraganglioma. Respir Med Case Rep. 2020; 30: 101092.-DOI: https://doi.org/10.1016/j.rmcr.2020.101092.

Itagaki K., Notsuda H., Suzuki T., et al. Combined left thoracoscopic and median sternotomy approach to resect aortopulmonary mediastinal paraganglioma following feeding artery embolization: a case report. Surg Case Rep. 2022; 8(1): 176.-DOI: https://doi.org/10.1186/s40792-022-01534-2.

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.