Evaluation of ovarian status in women who received anti-tumor therapy in childhood and adolescence
##article.numberofdownloads## 61
##article.numberofviews## 79
PDF (Русский)

Keywords

children
long-term effects of anti-tumor therapy
ovarian reserve
anti-Müllerian hormone

How to Cite

, , , , , , , & . (2014). Evaluation of ovarian status in women who received anti-tumor therapy in childhood and adolescence. Voprosy Onkologii, 60(3), 360–365. https://doi.org/10.37469/0507-3758-2014-60-3-360-365

Abstract

The paper presents the results of a study of the ovarian reserve in young women who received treatment for malignant tumors in childhood and adolescence and are in complete clinical remission. The function of the reproductive system was evaluated by serum concentrations of gonadotropins, estradiol, anti-Müllerian hormone (AMH) and inhibin B. The results were compared to the treatment, patients’ age at the beginning of therapy and at the time of the examination. AMH level in serum was the most informative indicator of ovarian reserve in patients treated for malignant tumors.
https://doi.org/10.37469/0507-3758-2014-60-3-360-365
##article.numberofdownloads## 61
##article.numberofviews## 79
PDF (Русский)

References

Кравченко Д.Н., Пароконная А.А., Нечушкин М.И. Принципы фармакологической защиты функции яичников // Клин. онкогематол. - 2011. - Т. 4. - N. 3. - P. 251-253.

Anderson R.A., Nelson S.M., Wallace W.H. Measuring antiM llerian hormone for the assessment of ovarian reserve: when and for whom is it indicated? // Maturitas. - 2012. - Vol. 71. - N. 1. - P. 28-33.

Bath L.E., Hamish W., Wallace B. and Critchley H.O.D. Late effects of the treatment of childhood cancer on the female reproductive system and the potential for fertility preservation // BJOG. - 2002. - Vol. 109. - N 2. - P. 107-114.

Behringer K., Breuer K., Reineke T et al. Secondary amenorrhea after Hodgkin’s lymphoma is influenced by age at treatment, stage of disease, chemotherapy regimen, and the use of oral contraceptives during therapy: a report from the German Hodgkin’s lymphoma study group // J. Clin. Oncol. - 2005. - Vol. 23. - N 30. - P. 7555-7564.

Beck-Peccoz P., Persani L. Premature ovarian failure // Orphanet J Rare. - 2006. - N. 1. - P. 1-9.

Brignardello E., Felicetti F., Castiglione A. et al. Endocrine health conditions in adult survivors of childhood cancer: the need for specialized adultfocused followup clinics // Eur J Endocrinol. - 2013. - Vol. 168. - N 3. - P. 465 -472.

Brougham M.F.H., Wallace W.H.B. Subfertility in children and young people treated for solid and haematological malignancies // Br J Haematol. - 2005. - Vol. 131. - N. 2. - P. 143-155.

Brydoy M., Foss S.D., Dahl O. et al. Gonadal dysfunction and fertility problems in cancer survivors // Acta Oncol. - 2007. - Vol. 46. - N 4. - P. 480-489.

Domingues T.S., Rocha A.M., Serafini P.C. Tests for ovarian reserve: reliability and utility // Curr Opin Obstet. Gyn. -2010. -Vol.22, N 4. - P. 271-276.

Donaldson S.S., Link M.P., Weinstein H.J. et al. Final results of a prospective clinical trial with VAMP and lowdose involved field radiation for children with lowrisk Hodgkin’s disease // J. Clin. Oncol. - 2007. Vol. 25. - No. 3. - P. 332-337.

EL-Shalakany A.H., Mohamed S. Ali, Abdelmaksoud A.A. et al. Ovarian function in female survivors of childhood malignancies // Ped Hematol Oncol. - 2013. - Vol. 30. - No. 4. - P. 328-335.

Fong S.L., Lugtenburg P.J., Schipper I. et al. Antim llerian hormone as a marker of ovarian function in women after chemotherapy and radiotherapy for haematological malignancies // Hum Reprod. - 2008. - Vol. 23. - N 3. - P. 674-678.

Giuseppe L., Attilio G., Edoardo D.N. et al. Ovarian function after cancer treatment in young women affected by Hodgkin disease // Hematol. - 2007. - Vol. 12. - N 2. - P. 141-147.

Johnston R.J., Wallace W.H.B. Normal ovarian function and assessment of ovarian reserve in the survivor of childhood cancer // Ped. Blood Cancer. - 2009. - Vol. 53. - No. 2. - P. 296-302.

Klein N., Illingworth P., Groome N. et al. Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: a study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstual cycles // J Clin Endocrinol Metab. - 1996. - Vol. 81. - P. 2742-2745.

Krawczuk Rybak M., Leszczynska E., Poznanska M., et al. AntiM llerian Hormone as a Sensitive Marker of Ovarian Function in Young // Cancer Surv Intern J Endocrinol. - 2013. - ID 125080. - 6 p.

Lunsford A.J., Whelan K., McCormick K., McLaren J.F. Antim llerian hormone as a measure of reproductive function in female childhood cancer survivors // Fertil Steril. - 2013. - Vol. 101. - Issue 1. - P. 227-231.

Miyoshi Y., Ohta H., Namba N. et al. Low serum concentrations of antim llerian hormone are common in 53 female childhood cancer survivors // Horm Res Paediatr. - 2013. - Vol. 79. - N 1. - P. 17-21.

Oeffinger K.C., Mertens A.C., Sklar C.A. et al. Chronic health conditions in adult survivors of childhood cancer // New Engl J Med. - 2006. - Vol. 355. - N 15. - P. 1572-1582.

Shalitin S., Laur E., Lebenthal Y. et al. Complications and components of the metabolic syndrome in survivors of childhood malignant nonbrain solid tumors // Horm Res Paediatr. - 2014. - Vol. 81. - N 1. - Vol. 81. - P. 32 -42.

Siviero Miachon A.A., Spinola Castro A.M., Guerra Junior G. Detection of metabolic syndrome features among childhood cancer survivors: A target to prevent disease // Vasc Health Risk Manag. - 2008. - Vol. 4. - N 4. - P. 825-836.

Sklar C.A., Mertens A.C., Mitby P. et al. Premature Menopause in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study // J.Natl.Cancer. Ints. - 2006. - Vol. 98. - N 13. - P. 890-896.

Sowers M.R., Eyvazzadeh A.D., McConnell D. et al. Anti-Mullerian hormone and inhibin B in the definition of ovarian aging and the menopause transition // J. Clin Endocrinol Metab. - 2008. - Vol. 93. - P. 3478-3483.

Thomas-Teinturier C., El Fayech C. Oberlin O et al. Age at menopause and its influencing factors in a cohort of survivors of childhood cancer: earlier but rarely premature // Hum Reprod. - 2013. Vol. 28. - N 2. - P. 488-495.

Van Beek R.D., Heuvel Eibrink M.M., Laven J.S.E. et al. Antim llerian hormone is a sensitive serum marker for gonadal function in women treated for Hodgkin’s lymphoma during childhood // J Clin Endocrinol Metab. - 2007. - Vol. 92. - N 10. - P. 3869-3874.

Visser J.A., Schipper I., Joop S.E. et al. Anti-M llerian hormone: an ovarian reserve marker in primary ovarian insufficiency // Nat Rev Endocrinol. - 2012. Vol. 10. - N 8. - P. 331-341

Zec I., TislaricMedenjak D., Megla Z.B., Kucak I. AntiMullerian hormone: a unique biochemical marker of gonadal development and fertility in humans // Biochem Med. - 2011. - Vol. 21, N 3. - P. 219-230.

All the Copyright statements for authors are present in the standart Publishing Agreement (Public Offer) to Publish an Article in an Academic Periodical 'Problems in oncology' ...