Breast cancer. De-Escalating Breast Cancer Surgery.
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Keywords

breast cancer
neoadjuvant systemic therapy
vacuum-assisted biopsy
refusal of breast surgery

How to Cite

Mortada, V., Krivorotko, P., Semiglazov, V., Pesotsky, R., Emelyanov, A., Mortada, M., Amirov, N., Channov, V., Tabagua, T., Gigolaeva, L., Yerechshenko, S., Komyahov, A., Nikolaev, K., Zernov, K., Ziltsova, E., Bessonov, A., Bondarchuk, Y., Enaldieva, D., Semiglazov, V., Busko, K. ., Novikov, S., Kanaev, S., & Belyaev, A. (2022). Breast cancer. De-Escalating Breast Cancer Surgery. Voprosy Onkologii, 68(3), 273–285. https://doi.org/10.37469/0507-3758-2022-68-3-273-285

Abstract

The high rates of pathologic complete response (pCR) after modern systemic therapy observed in patients with HER2-positive and triple-negative breast cancer led to the fact that there was a tendency to reduce surgical activity up to the complete refusal of breast surgery subject to the assessment of complete pathological regression using both radiation diagnostic methods and methods of morphological verification of the tumor bed, such as vacuum-assisted biopsy , and accurate core needle biopsy.

This review article summarizes all available data on how to morphologically assess complete pathomorphological  response (p CR)  after neoadjuvant systemic therapy using core needle biopsies and vacuum-assisted biopsy .

 

https://doi.org/10.37469/0507-3758-2022-68-3-273-285
##article.numberofdownloads## 223
##article.numberofviews## 518
pdf (Русский)

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