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Long term results of treatment of patients with locally advanced breast carcinoma with the use of mixed photon-neutron therapy (PNT) are presented. Among 201 patients with locally advanced breast cancer receiving radiation therapy, in 95 of them it was implemented as a combination of photon and neutron radiation therapy and in 106 - in the form of megavolt photon therapy (PT). Comparative evaluation of the long-term results of treatment proved the superiority of PNT. The immediate effect after PNT in the form of complete and partial response of tumor was registered in 87.4 %, and after PT - in 49 % of cases. Five-year and ten-year survival rates without signs of disease after PNT were 58.1 % and 29.5 %, and after PT -36.4 % and 7.4 % respectively. Substantial differences in toxicity of techniques were not observed.References
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