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Abstract
For treatment of cancer of the thoracic esophagus, the method of neoadjuvant chemoradiotherapy (CRT) with a use of intraluminal brachytherapy (BT) was performed. The study included 51 patients (mean age 56,9 ± 4,3 years). The length of the primary tumor up to 6 cm was determined in 18 patients, more than 6 cm - 33 patients. CRT included three BT sessions (7Gy X 3; q7d) and two cycles of chemotherapy (PF; q28d). After CRT in 30 (62.4 %) patients there was marked a complete or partial radiological tumor regression. In 40-45 days after CRT surgery performed. Subtotal resection of esophagus of the Lewis type was performed in 29 cases, transtracheal extirpation of the esophagus - in 2, minimally invasive esophagectomy - in 17 cases. Postoperative complications occurred in 22 (44 %) patients; one patient died (2 %). In 11 (23 %) patients morphological investigation revealed a complete regression of the primary tumor. Thus, a use of intraluminal BT in combination with chemotherapy in many cases promoted reducing the size of the primary tumor of the esophagus, which was an effective factor in improving surgical results.References
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