Abstract
Karyotypes of 9 malignant melanoma patients has been described. It is ascertained that most often the damage is observed in chromosomes 1, 6, 7, 9 and 17, which is consistent with the data in the literature. Besides chromosomes 5 and 13 are also often involved in different rearrangements. Recurring aberrations are not discovered. Any correlation between survival and non-recurrent chromosomal aberrations is not discovered.References
An International System for Human Cytogenetic Nomenclature, 2009. Recommendations of International Standing Commitee on Human Cytogenetic Nomenclature / Eds. L. Shaffer, N. Tommerup. - 2009, Basel: S. Karger. - 138 p.
Blokx W.A., van Dijk M.C., Ruiter D.J. Molecular cytogenetics of cutaneous melanocytic lesions - diagnostic, prognostic and therapeutic aspects // Histopathology. - 2010. - Vol. 56 (1). - P. 121-132.
Busam K.J., Fang X., Jhanwar S., Lacouture M. Diagnosis of blue nevus-like metastatic uveal melanoma confirmed by fluorescence in situ hybridization (FISH) for monosomy // J. Cutan Pathol. - 2010. - Vol. 39 (6). - P. 621-625.
Chin L., Garraway L.A., Fisher D.E. Malignant melanoma: genetics and therapeutics in the genomic era // Genes Dev. - 2006. - Vol. 20. - P. 2149-2182.
Curtin J., Fridllyand J., Kageshita T. et al. Distinct sets of genetics alterations in melanoma // Engl. J. Med. - 2005. - Vol. 353. - P. 2135-2147.
Freshney R.I. Culture of animal cells: A manual of basic technique and specialized applications. - 2010. - N.-Y. -Chichester: Wiley & Sons, publ. - 732 p.
Gerami P., Mafee M., Lurtsbarapa T. et al. Sensitivity of fluorescence in situ hybridization for melanoma diagnosis using RREB1, MYB, Cep6, and 11q13 probes in melanoma subtypes // Arch Dermatol. - 2010. - Vol. 146 (3). - P. 273-278.
Gerami P., Jewell S., Pouryazdanparast P., Wayne J.D., Haghighart Z., Busam K.J., Rademaker A., Morrison L., 2011. Copy number gains in 11g13 and 8g24 are highly linked to prognosis in cutaneous malignant melanoma. J. Mol. Diagn. 13 (3): 352-358.
Gerami P., Li G., Pouryazdanparast, Blondin B. et al. A highly specific and discriminatory FISH assay for distinguishing between benign and malignant melanocytic neoplasms // Am J Surg Pathol. - 2012. - Vol. 36 (6). - P. 808-817.
Gersen S.L., Keagle M.B. 1999. The principles of clinical cytogenetics. Totowa, New Jersey, USA: Humana Press. 557 p.
Gleeson G., Larkin A., Horgan N., Kennedy S. Evaluation of chromogenic in situ hybridization for the determination of monosomy 3 in uveal melanoma // Arch. Pathol. Lab. Med. - 2014 - Vol. 138 (5). - P. 664-670.
Guitart J., Haghighat Z., Newman M. Assessment of copy number status of chromosomes 6 and 11 by FISH provides independent prognostic information in primary melanoma // Am J Surg Pathol. - 2011. - Vol. 35. - P. 1146-1150.
Guo R., Wang X., Chen J. et al. Comparative genomic hybridization in a case of melanoma that loses expression of S100, HMB45, Melan A and tyrosinase in metastasis // Int. J. Clin. Exp. Pathol. - 2013. - Vol. 15 (7). - P. 468 -473.
Harbst K., Staaf J., Måsbäck A. et al. Multiple metastases from cutaneous malignant melanoma patients may display heterogeneous genomic and epigenomic patterns // MelanomaRes. - 2010. - Vol. 20 (5). - P. 381-391.
Heim S., Mitelman F. Melanocytictumors / In: Cancer Cytogenetics. Third edition. -2009, Canada: Wiley-Blackwel. - P. 644-647.
Jonsson G., Dahl S., Staaf J., Sandberg T. Genomic profiling of malignant melanoma using tiling-resolution array CGH // Oncogene. - 2007. - Vol. 26. - P. 4738-4788.
Klein C.A. Gene expression signature, cancer cell evolution and metastatic progression // Cell Cycle. -2004. - Vol. 3. - P. 29-31.
Lachiewicz A.M., Berwick A., Wiggins C.L., Thomas N.E. Epidemiologic Support for Melanoma Heterogeneity Using the Surveillance, Epidemiology, and End Results Program // J. Invest. Dermatol. - 2008. - Vol. 128. - P. 243-245.
Levin D.B., Wilson K., Valadares de Amorim G. et al. Detection of p53 mutation in benign and dysplastic nevi // Cancer Res. - 1995. - Vol. 55 (19). - P. 4278-4282.
Lewis T.B., Robison J.E., Bastien R. Molecular classification of melanoma using real-time quantitative reverse transcriptase-polymerase chain reaction // Cancer. - 2005. - Vol. 104. - P. 1678-1686.
Miele M., Robertson G., Lee G., Coleman A. Metastasis suppressed, but tumorigenicity and local invasiveness unaffectedin the human melanoma cell line Me 1JuSo after introduction of human chromosomes 1 or 6 // Mol. Carcinogenesis. - 1996. - Vol. 15 (2). - P. 284-299.
Moore S.R., Persons D.L., Sosman J.A. Detection of Copy Number Alterations in Metastatic Melanoma by a DNA Fluorescence In situ Hybridization Probe Panel and Array Comparative Genomic Hybridization: A Southwest Oncology Group Study (S9431) // Clin. Cancer Res. - 2008. - Vol. 14. - P. 2927-2935.
Nelson M., Radmacher M., Simon R. et al. Chromosome abnormalities in malignant melanoma: clinical significance of nonrandom chromosome abnormalities in 206 cases // Cancer. Genet. Cytogenet. - 2000. - Vol. 122 (1). - P. 101-109.
North J.P., Vetto J.T., Murali R. et al. Assessment of copy number status of chromosome 6 and 11 by FISH provides independent prognostic information in primary melanoma // Am.J. Surg. Pathol. - 2011. - Vol. 35 (8). - P. 1146 -1150.
Parmiter A., Nowell P. The cytogenetics of human malignant melanoma and premalignant lesions / In: Malignant melanoma: Biology, Diagnosis and Therapy. - 1988, Boston: Kluwer Academic Publishers. - P. 47-61.
Poetscha M., Dittbernerb T., Woenckhaus C. Can different genetic changes characterize histogenetic subtypes and biologic behavior in sporadic malignant melanoma of the skin? // CMLS, Cell. Mol. Life Sci. - 2003. - Vol. 60. - P. 1923-1932.
Pujana M., Ruiz A., Badenas C. et al. Molecular characterization of a t(9;12)(p21;q13) balanced chromosome translocation in combination with integrative genomics analysis identifies C9orf14 as candidate tumor-supressor // Genes Chromosomes Cancer. - 2007. - Vol. 46 (1). - P. 155-162.
Santos G.C., Zielenska M., Prasad M., Squire J.A. Chromosome 6p amplification and cancer progression // J. Clin. Pathol. - 2007. - Vol. 60(1). - P. 1-7.
Sobey G., Gwuarrell O., Willams S., McGrath H.M. Mosaic chromosome 6 trisomy in an epidermal nevus // Pediator. Dermatol. - 2007. - Vol. 24 (2). - P. 144-146.
Urosevic M., Braun B., Willers J. Expression of melanoma-associated antigens in melanoma cell cultures // Exp. Dermatol. - 2005. - Vol. 14 (7). - P. 491-497.
Welch D.R., Chen P., Miele M. E. et al. Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity // Oncogene. - 1994. - Vol. 9. - P. 255-262.
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