Circular resection margin - the actual predictor of surgical treatment for rectal cancer
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Keywords

rectal cancer
circular resection margin
results of treatment
prognostic factors

How to Cite

, , , , , & . (2014). Circular resection margin - the actual predictor of surgical treatment for rectal cancer. Voprosy Onkologii, 60(6), 679–682. https://doi.org/10.37469/0507-3758-2014-60-6-679-682

Abstract

Treatment for rectal cancer has significantly changed in recent decades. The widespread adoption of total mesorectumectomy combined with the extensive use of radiation and chemotherapy has led to improved prognosis. One of the most important predictors of the effectiveness of surgical treatment for rectal cancer is the status of the circular resection margin. Since the description of its clinical significance in 1986, the involvement of the circular edge is associated with a poor prognosis putting long-term results of treatment depending on the evaluation of the quality of surgery. However up to date diagnostics of circular resection margin status is not included in standards of morphological studies.
https://doi.org/10.37469/0507-3758-2014-60-6-679-682
PDF (Русский)

References

Birbeck K.F., Macklin C.P., Tiffin N.J. et al. Rates of circumferential resection margin involvement vary between surgeons and predict outcomes in rectal cancer surgery // Ann. Surg. - 2002. - Vol. 235, № 4. - P. 449-457.

Breukink S.O., Grond A.J., Pierie J.P. et al. Laparoscopic vs open total mesorectal excision for rectal cancer: an evaluation of the mesorectum’s macroscopic quality // Surg. Endosc. - 2003. - Vol. 19, № 3. - P. 307-310.

Gollins S. Radiation, chemotherapy and biological therapy in the curative treatment of locally advanced rectal cancer // Colorectal Dis. - 2010. - Vol. 12, № 2. - P. 2-24.

Gosens M.J., van Krieken J.H., Marijnen C.A. et al. Improvement of staging by combining tumor and treatment parameters: the value for prognostication in rectal cancer // Clin. Gastroenterol. Hepatol. - 2007. - Vol. 5, № 8. - P. 997-1003.

Guillou P.J., Quirke P., Thorpe H. et al. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial // Lancet. - 2005. - Vol. 365, № 9472. - P. 1718-1726.

de Haas-Kock D.F., Baeten C.G., Jager J.J. et al. Prognostic significance of radial margins of clearance in rectal cancer // Br. J. Surg. - 1996. - Vol. 83, № 6. - P. 781-785.

Macadam R., Yeomans N., Wilson J. et al. Factors affecting morbidity, mortality and survival in patients undergoing surgery for rectal cancer in a district general hospital // Ann. R. Coll. Surg. Engl. - 2005. - Vol. 87, № 5. - P. 334-338.

Mawdsley S., Glynne-Jones R., Grainger J. et al. Can histopathologic assessment of circumferential margin after preoperative pelvic chemoradiotherapy for T3-T4 rectal cancer predict for 3-year disease-free survival? // Int. J. Radiat. Oncol. Biol. Phys. - 2005. - Vol. 63, № 3. - P. 745-752.

Moore H.G., Gittleman A.E., Minsky B.D. et al. Rate of pathologic complete response with increased interval between preoperative combined modality therapy and rectal cancer resection // Dis. Colon Rectum - 2004. - Vol. 47, № 3. - P. 279-286.

Moriya Y., Hojo K., Sawada T. et al. Significance of lateral node dissection for advanced rectal carcinoma at or below the peritoneal reflection // Dis. Colon Rectum. - 1989. - Vol. 32, № 4. - P. 307-315.

Morris E.J., Maughan N.J., Forman D. et al. Identifying stage III colorectal cancer patients: The influence of the patient, surgeon, and pathologist // J. Clin. Oncol. - 2007. - Vol. 25, № 18. - P. 2573-2579.

Nagtegaal I.D., Gosens M.J., Marijnen C.A. et al. Combinations of tumor and treatment parameters are more discriminative for prognosis than the present TNM system in rectal cancer // J. Clin. Oncol. - 2007. - Vol. 25, № 13. - P. 1647-1650.

Nagtegaal I.D., Marijnen C.A., Kranenbarg E.K. et al. Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit // Am. J. Surg. Pathol. - 2002. - Vol. 26, № 3. - P. 350-357.

Nagtegaal I.D., Quirke P. What is the role for the circumferential margin in the modern treatment of rectal cancer? // J. Clin. Oncol. - 2008. - Vol. 26, № 2. - P. 303-312.

Nagtegaal I.D., van de Velde C.J., Marijnen C.A. et al. Low rectal cancer: a call for a change of approach in abdominoperineal resection // J. Clin. Oncol. - 2005. - Vol. 23, № 36. - P. 9257-9264.

Ng I.O., Luk I.S., Yuen S.T. et al. Surgical lateral clearance in resected rectal carcinomas. A. multivariate analysis of clinicopathologic features // Cancer. - 1993. - Vol. 71, № 6. - P. 1972-1976.

Phang P.T., MacFarlane J.K., Taylor R.H. et al. Effects of positive resection margin and tumor distance from anus on rectal cancer treatment outcomes // Am. J. Surg. - 2002. - Vol. 183, № 5. - P. 504-508.

Quirke P., Durdey P., Dixon M.F. et al. Local recurrence of rectal adenocarcinoma due to inadequate surgical resection. Histopathological study of lateral tumour spread and surgical excision // Lancet. - 1986. -Vol. 328, № 8514. - P. 996-999.

Quirke P., Steele R., Monson J. et al. Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial // Lancet. - 2009. - Vol. 373, № 9666. - P. 821-828.

Sebag-Montefiore D., Stephens R.J., Steele R. et al. Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CtG C016): a multicentre, randomised trial // Lancet. - 2009. - Vol. 373, № 9666. - P. 811820.

Stocchi L., Nelson H., Sargent D.J. et al. Impact of surgical and pathologic variables in rectal cancer: A. United States community and cooperative group report // J. Clin. Oncol. - 2001. - Vol. 19, № 18. - P. 3895-3902.

Tekkis P.P., Heriot A.G., Smith J. et al. Comparison of circumferential margin involvement between restorative and nonrestorative resections for rectal cancer // Colorectal Dis. - 2005. - Vol. 7, № 4. - P. 369-374.

Wang Z., Zhou Z.G., Wang C. et al. Regional micrometastasis of low rectal cancer in mesorectum: a study utilizing HE stain on whole-mount section and ISH analyses on tissue microarray // Cancer Invest. - 2006. - Vol. 24, № 4. - F1. 374-381.

Wibe A. A national strategic change in treatment policy for rectal cancer - implementation of total mesorectal excision as routine treatment in Norway. A national audit / A. Wibe, B.M. ller, J. Norstein [et al.] // Dis. Colon Rectum. - 2002. - Vol. 45, № 7. - P. 857-366.

Wibe A., Rendedal P.R., Svensson E. et al. Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer // Br. J. Surg. - 2002. - Vol. 89, № 3. - P. 327-334.

Wibe A., Syse A., Andersen E. et al. Oncological outcomes after total mesorectal excision for cure for cancer of the lower rectum: anterior vs. abdominoperineal resection // Dis. Colon Rectum - 2004. - Vol. 47, № 1. - P. 48-58.

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