Abstract
Hormone-sensitive breast cancer (HSC) is a common neoplastic disorder. HSC treatment involves endocrine therapy, which is strongly associated with joint pain. The cause of arthralgia in these patients is still unclear, but there are indications that it may be inflammation driven. The article presents the current understanding of this issue and highlights the pathophysiological mechanisms of the autoimmune and autoinflammatory pathology development in BC patients receiving estrogen deprivation therapy.
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