INFORMATIVE VALUE OF POSITRON EMISSION TOMOGRAPHY WITH 18F-FDG IN DIAGNOSTICS AND STAGING OF PATIENTS WITH HODGKIN’S LYMPHOMA
PDF (Русский)

Keywords

Hodgkin's lymphoma
Pet with F-FDG
CT
lymphatic nodules
extranodal organs

How to Cite

(2013). INFORMATIVE VALUE OF POSITRON EMISSION TOMOGRAPHY WITH 18F-FDG IN DIAGNOSTICS AND STAGING OF PATIENTS WITH HODGKIN’S LYMPHOMA. Voprosy Onkologii, 70(2), 470–474. https://doi.org/10.37469/0507-3758-2013-59-4-470-474

Abstract

Eighty nine patients with newly diagnosed Hodgkin's lymphoma (HL) underwent conventional staging methods including computer tomography (CT) as well as positron emission tomography (PET) with 18F-FDG. All lesions in PET with 18F-FDG and CT were correlated to each other. Identical results of PET and CT in identifying pathological focuses were obtained in 220 anatomical regions. Discordant results of PET and CT were determined in 59 anatomical areas. In 27 cases data of both methods were equivocal and could be regarded as normal or pathological. Analysis of the results showed the sensitivity, specificity and diagnostic accuracy of PET were higher than the diagnostic efficacy of CT in the detection of pathological lymph nodes, extranodal organs as well as in localization of disease above and below diaphragm. The sensitivity of CT was lower in the detection of pathological lymph node and extranodal organs below the diaphragm — 68,5%. In accordance with the results of PET the stage of disease and treatment tactics were changed 11.2% patients.
https://doi.org/10.37469/0507-3758-2013-59-4-470-474
PDF (Русский)

References

Переводчикова Н.И. Руководство по химиотерапии опухолевых заболеваний. — М., Практическая медицина, 2005. — 704 с.

Buchmann I., Reinhardt M., Elsner K. et al. 2-(Fluorine-18) Fluoro-2-Deoxy_D-Glucose Positron Emission Tomography in the Detection and staging of malignant lymphoma. A bicenter trial // Cancer. Philad. — 2001. — Vol. 91. — P. 889-899.

Castellino R.A. Diagnostic radiology // The lymphomas Ed. by G.P. Cancellos, T.A. Lister, J.L. Sklar. Philadelphia: Saunders Company. — 1998. — P. 187-206.

Collins C.D. PET in lymphoma // Cancer Imaging. — 2006. — Vol. 6. — P. 63-70.

Duhmke E., Diehl V., Loeffler M. et al. Randomized trial with early-stage Hodgkin's disease testing 30 Gy vs 40 Gy extended field radiotherapy alone // Int. J. Radiat. Oncol. Biol. Phys. — 1996. — Vol. 36. — P. 305-310.

Even-Sapir E. Imaging of malignant bone involvement by morphologic, scintigraphic, and hybrid modalities // J. Nucl. Med. — 2005. — Vol. 46. — P. 1356-1367.

Freudenberg L.S., Antoch G., Schutt P., et al. FDG-PET/CT in re-staging of patients with lymphoma // Eur J Nucl Med Mol Imaging. — 2004. — Vol. 31. — P. 325-329.

Gospodarowicz M.K. Hodgkin's lymphoma — Patient Assessment and Staging // Cancer J. — 2009. — Vol. 15. — P. 138-142.

Gossmann A., Eich H.T., Engert A. et al. CT and MR imaging in Hodgkin's disease — present and future // Europ. J. Haematol. — 2005. — Vol. 75. — P. 83-89.

Henry-Amar M., Joly F. Late complications after Hodgkin’s disease // Ann Oncol. — 1996. — Vol. 7. — P. 115-126.

Kwee T.C., Kwee R.M., Rutger A.J.N. Imaging in staging of malignant lymphoma: a systematic review // Blood. — 2008. — Vol. 111. — P. 504-516.

Kwee T.C., John M.H. de Klerk, Nievelstein A.J. Imaging of bone marrow involvement in lymphoma: state of art and future directions // The Scientific World J. — 2011. — Vol. 11. — P. 391-402.

Shields A.F., Porter B.A., Churchley S. et al. The detection of bone marrow involvement by lymphoma using magnetic resonance imaging // J Clin Oncol. — 1987. — Vol. 5. — P. 225-230.

Shipp M.A. Prognostic factors in aggressive non-Hodgkin’s lymphoma: who has «high-risk» disease? // Blood. — 1994. — Vol. 83. — P. 1165-1173.

Stein R.S., Golomb H.M., Diggs C.H., et al. Anatomic substages of stage IIIA Hodgkin s disease. A collaborative study // Ann Intern Med. — 1980. — Vol. 92. — P. 159-165.

Vinnicombe S.J., Reznek R.H. Computerised tomography in the staging of Hodgkin’s disease and non-Hodgkin’s lymphoma // Europ J Nucl Med Mol Imaging. — 2003. — Vol. 30. — P. 42-55.

All the Copyright statements for authors are present in the standart Publishing Agreement (Public Offer) to Publish an Article in an Academic Periodical 'Problems in oncology' ...