Vol. 70 No. 4 (2024), REVIEWS

Vol. 70 No. 4 (2024)

Atypical Teratoid/Rhabdoid Tumors of Central Nervous System in Children. Literature Re-view

REVIEWS

https://doi.org/10.37469/0507-3758-2024-70-4-622-632

Published 06.09.2024

Elizaveta Vladimirovna Tyurina⁺⁻
Timur T. Valiev⁺⁻
Ella Vyacheslavovna Kumirova⁺⁻
Olga Mikhailovna Romantsova⁺⁻
Svetlana Rafaelevna Varfolomeeva⁺⁻

Elizaveta Vladimirovna Tyurina

N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia; 23 Kashirskoe Shosse, Moscow, 115478, Russia

https://orcid.org/0000-0003-4019-5247

Timur T. Valiev

N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia, Mos-cow, Russia

https://orcid.org/0000-0002-1469-2365

Ella Vyacheslavovna Kumirova

Morozovskaya Children’s Clinical Hospital, Department of Health in Moscow

https://orcid.org/0000-0001-6125-2410

Olga Mikhailovna Romantsova

N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia

https://orcid.org/0000-0002-2310-0106

Svetlana Rafaelevna Varfolomeeva

N.N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia

https://orcid.org/0000-0001-6131-1783

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##article.numberofviews## 192

pdf (Русский)

Keywords

atypical teratoid/rhabdoid tumors
tumors of the central nervous system
young children
treatment

How to Cite

Tyurina, E. V., Valiev, T. T., Kumirova, E. V., Romantsova, O. M., & Varfolomeeva, S. R. (2024). Atypical Teratoid/Rhabdoid Tumors of Central Nervous System in Children. Literature Re-view. Voprosy Onkologii, 70(4), 622–632. https://doi.org/10.37469/0507-3758-2024-70-4-622-632

Abstract

Atypical teratoid/rhabdoid tumors (ATRT) are highly aggressive malignant tumors of the central nervous system (CNS), predominantly diagnosed in young children. Despite complex treatment approaches including surgery, chemotherapy, radiotherapy, targeted therapy and immunotherapy, outcomes remain extremely unfavorable. Modern epidemiological and molecular biological research aims to study the etiology of tumors, the molecular characteristics of malignant neoplasms, and to determine the possibility of using targeted drugs, which will help to increase the understanding of the structure of the process and give a chance of improving the survival of patients with ATRT.

https://doi.org/10.37469/0507-3758-2024-70-4-622-632

##article.numberofdownloads## 105

##article.numberofviews## 192

pdf (Русский)

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