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Nowadays the most popular and justified, from oncological positions, method of treatment for soft tissue sarcomas is a combined approach with the use of conservative surgery followed by postoperative radiation therapy. In this regard, intraoperative radiation therapy (IORT) in a single dose of 1020 Gy is a method that optimizes the role of radiation therapy in treatment of this pathology allowing precise localization of radiation zone within the “tumor bed”, thereby minimizing damage of normal tissues and critical organs. The aim of the study was to investigate the effect of IORT on the frequency and structure of post-operative complications. Testing group (n = 49) was compared to the group without IORT (n = 57) and group with only surgery (n = 171). According to the study it was not obtained statistically significant differences in the incidence of postoperative complications in the groups (p = 0,57), not marked influence on the structure of post-operative complications.References
Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ в 2010 г. // Вестн. РОНЦ им. Н.Н. Блохина. — 2012. — С. 155-158.
Мусабаева Л.И., Нечитайло М.Н., Лисин В.А. Результаты комбинированного лечения с интраоперационной лучевой терапией и дистанционной гамма-терапией злокачественных новообразований отдельных локализаций // Мед. радиол. — 2005. - № 2. - С. 46-55.
Скоропад В.Ю., Бердов Б.А. История и современное состояние клинического использования интраоперационной лучевой терапии у больных раком желудка // Рос. онкол. журнал. — 1998. — № 5. — С. 55-58.
Cleator S.J., Cottrill C., Harmer C. Pattern of local recurrence after conservative surgery and radiotherapy for soft tissue sarcoma // Sarcoma. — 2001. — Vol. 5. — P. 83-88.
Calvo F.A., Meirino R.M., Gunderson L.L., Willett C.G. Intraoperative radiation therapy // Principles and Practice of Radiation Oncology, Philadelphia. — Lippincott. — 2004. -4th Ed. eds. Perez C.A. et al. - P. 428-456.
Tran P.T., Hara W., Su Z., Lin H.J. et al. Intraoperative Radiation Therapy for Locally Advanced and Recurrent Soft-Tissue Sarcomas in Adults // Int. J. Radiat., Oncol., Biol., Physics. -2008. - Vol. 72. - P. 1146-1153.
Lehnert T., Schwarzbach M., Willeke F. et al. Intraoperative radiotherapy for primary and locally recurrent soft tissue sarcoma:morbidity and long-term prgnosis // Europ J Surg. Oncol. — 2000. Vol. -26 (Suppl A). — P. 21-24.
Niewald M., Fleckenstein J., Licht N., Bleuzen C. Intraoperative radiotherapy (IORT) combined with external beam radiotherapy (EBRT) for soft-tissue sarcomas--a retrospective evaluation of the Homburg experience in the years 1995-2007 // Radiat Oncol. — 2009. - Vol. 26. - P. 4-32.
Yang J.C., Chang A.E., Baker A.R. et al. Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity // J. Clin. Oncol. - 1998. - Vol. 16. - P. 197203.
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