Keywords
How to Cite
Abstract
At the N.N. Petrov Research Institute of Oncology from 1986 to 2015 there were performed 445 radical operations for skin melanoma of upper and lower extremities in patients aged 18 to 87 years. The present study analyzed data of 40 patients with morphologically confirmed diagnosis of “subungual melanoma” (SM). Long-term results and causes of death were evaluated in all operated patients. A 1-year survival rate of SM patients, whatever stage of disease was 90%, a 5-year overall survival rate - 47%, while only 20% of patients have survived a 10-year line. Overall survival median was 55 ± 9.4 months (95% CI, 36.4-73.5). The probability of death of radically operated SM patients in the next 5 years after surgical treatment from co-morbidities did not exceed 10%. SM patients had the worst prognosis as compared with patients with skin melanoma of upper and lower limbs (p = 0,0001).References
Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ в 2007 г. // Вестн. РОНЦ им. Н.Н. Блохина. - 2009. - Т. 20. - № 3. - 158 с.
Демидов Л.В., Харатишвили Т.К., Периханян Ф.К. Акральная меланома кожи. Эпидемиология, клиника, диагностика, лечение, прогноз // Вестник РОНЦ имени Н.Н. Блохина РАМН. - 2003. - Т. 14. - № 2/1. - С. 72 - 75.
Мяснянкин М.Ю., Гафтон Г.И., Анисимов В.В. и др. Акральная лентигинозная меланома: современное состояние проблемы // Вопр. онкол. - 2015. - Т. 61 (4). - С. 563-570.
Albreski D, Brett Sloan S. Melanoma of the feet: misdiagnosed and misunderstood // Clin. Dermatol. - 2009. - Vol. 2009. - P. 556-563.
Bradford PT, Goldstein AM, McMaster ML et al. Acral len-tiginous melanoma. Incidence and survival pattern in the United States, 1986-2005 // Arch Dermatol. - 2009. -Vol. 145. - P. 427-434.
Chang J.W., Yeh K.Y, Wang C.H. et al. Malignant melanoma in Taiwan: a prognostic study of 181 cases // Melanoma Res. - 2004. - Vol. 14 - P. 537-541
Hutchinson J. Melanosis often not black: melanotic whitlow // Br med J. - 1886. - Vol. 1 - P. 491-494.
Kovich O.I., Soldano A.C. Clinical pathologic correlations for diagnosis and treatment of nail disorders // Dermatol. Ther. - 2007. - Vol. 20. - P. 11-16.
Marsden JR, Newton-Bishop JA, Burrows L et al. Revised UK guidelines for the management of cutaneous melanoma // J. Plast Reconstr Aesthet Surg. - 2010. - Vol. 63. - P1401-1419.
Phan A, Touzet S, Dalle S et al. Acral lentiginous melanoma: a clinicoprognostic study of 126 cases // Br. J. Dermatol. - 2006. - Vol. 155. - P 561-569.
Ruben B.S. Pigmented lesions of the nail unit: clinical and histopathologic features // Semin. Cutan. Med. Surg. - 2010. - Vol. 29. - P 148 - 158.
Soundry E, Gutman H, Feinmesser M et al. «Gloves-and-socks» melanoma: does histology make a difference? // Dermatol Surg. - 2008. - Vol. 34. - P. 1372-1378.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
© АННМО «Вопросы онкологии», Copyright (c) 2017