POSSIBLE CANINE OLFACTORY DETECTION OF BREAST CANCER
PDF (Русский)

Keywords

BREAST CANCER
CYNOLOGY
OTHORHINOLOGY
DIFFERENTIAL DIAGNOSIS
SCREENING

How to Cite

Ivanov, A., Sidorovich, G., Osipov, V., Trofimenko, Y., Astakhov, D., Kapitonova, N., Reshotko, V., & Polyushkin, D. (2018). POSSIBLE CANINE OLFACTORY DETECTION OF BREAST CANCER. Voprosy Onkologii, 64(5), 620–624. https://doi.org/10.37469/0507-3758-2018-64-5-620-624

Abstract

There is presented a possibility of canine otorhologic diagnosis of breast cancer based on presentation of odour material to service dogs: venous blood, urine and sweatfat secretions of female patients. The examination of odour material of ill women and control groups the sensitivity of the test was at the level of 0,94-0,98, specificity of 0,92 and 1,0 the predictive value of a positive result of 0,96-1,0 and negative 0,94-1,0, which significantly exceeded the diagnostic capabilities of mammography. On the basis of otorhologic study of sweatfat secretions there was showed high specificity of identifying patients with breast cancer among some other types of pathology including nodal mastopathy. A possibility of using olfactory capabilities of dogs when organizing mass screening tests is discussed.
https://doi.org/10.37469/0507-3758-2018-64-5-620-624
PDF (Русский)

References

Комарова Л.Е. Скрининг рака молочной железы // Medicum Consilium. - 2002. - Т. 4. - № 2.

Панфилов П.Е. Основные принципы обеспечения достоверности исследования запаховых следов человека с использованием собак - детекторов в судебной экспертизе. -М.- Юрлитинформ, 2007.

Семиглазов В.Ф., Семиглазов В.В. Скрининг рака молочной железы // Практическая онкология. - 2011. - № 2. - С. 60-65.

Чиссов В.И., Старинский В.В., Петрова Г.В. Злокачественные новообразования в России в 2010 году. - М., 2012.

Amundsen Т., Sundstrom S., Buvik T. et al. Can dogs smell lung cancer? First study using exhaled breath and urine screening in unselected patients with suspected lung cancer // Acta Oncologica. - 2014. - Vol. 53. - Р 307-315.

Carney P.A., Miglioretti D.L., Yankaskas B.P et al. Individual and combined effects of age, breast density and hormone replacement therapy use on the accuracy of screening mammography // Ann. Int. Med. - 2003. - Vol. 138 (3).

Church J., Williams H. Another sniffer dog for the clinic? // Lancet. - 2001. - Vol. 358 (9285). - P. 930-930. - DOI: 10.1016/S0140-6736(01)06065-2

Cornu J.N., Cancel-Tassin G., Ondet V. et al. Olfactory detection of prostate cancer by dogs sniffing urine: a step forward in early diagnosis // European Urology. - 2011. - Vol. 59. - Р 197-201.

Dogs Smell Cancer in Patients' Breath, Study Shows // National Geographic News. -2006.

Ehmann R., Boedeker E., Friedrich U. et al. Canine scent detection in the diagnosis of lung cancer: Revisiting a puzzling phenomenon // Eur Respir J. - 2011. - Vol. 39 (3). - P. 669-76. - DOI: 10.1083/09031936.00051711

McCulloch M., Jezierski T., Broffman M. et al. Diagnostic accuracy of canine scent detection in early - and late-stage lung and breast cancers // Integrative cancer therapies. - 2006. - Vol. 5 (1). - P. 30-9. - DOI: 10.1177/1534735405285096

Reses L.A., Eisner M.P, Kosary C.L. et al. SEER Cancer Statistics Review, 1973 - 1999. - Bethesda, Md: National Cancer Institute, 2002.

Sonoda H., Kohnoe S., Yamazato T. Colorectal cancer screening with odour material by canine scent detection // Gut. - 2011. - Vol. 60. - Р 814-819.

Williams H., Pembroke A. Sniffer dogs in the melanoma clinic? // Lancet. - 1989. - Vol. 1(8640). - P 734. - PMID 2564551. DOI: 10.1016/S0140-6736(89)92257-5

Willis C.M., Church S.M., Guest C.M. Olfactory detection of human bladder cancer by dogs: proof of principle study // British Medical Journal. - 2004. - Vol. 329. - Р. 712.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

© АННМО «Вопросы онкологии», Copyright (c) 2018