РОЛЬ СОСУДИСТОГО МИКРООКРУЖЕНИЯ В СТАНОВЛЕНИИ И РАЗВИТИИ ОПУХОЛЕЙ ГОЛОВНОГО МОЗГА
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Ключевые слова

АНГИОГЕНЕЗ
ПЕРИВАСКУЛЯРНАЯ НИША
ОПУХОЛЕВОЕ МИКРООКРУЖЕНИЕ
ГЛИАЛЬНЫЕ СТВОЛОВЫЕ КЛЕТКИ

Как цитировать

Доросевич, А., & Бузган, Н. (2018). РОЛЬ СОСУДИСТОГО МИКРООКРУЖЕНИЯ В СТАНОВЛЕНИИ И РАЗВИТИИ ОПУХОЛЕЙ ГОЛОВНОГО МОЗГА. Вопросы онкологии, 64(5), 570–577. https://doi.org/10.37469/0507-3758-2018-64-5-570-577

Аннотация

Процессы неоваскуляризации являются ключевыми для роста и распространения опухолевых клеток. В данной статье описаны уникальные паттерны ангиогенеза, которые считаются специфическими исключительно для опухолей головного мозга. В настоящее время все большее значение в глазах исследователей приобретает роль специализированных периваскулярных ниш в развитии онкологических процессов головного мозга. Периваскулярные ниши играют решающую роль в межклеточных взаимовлияниях между резидентными клеточными линиями при развитии опухолевого процесса, а также являются источником опухолевых стволовых клеток.
https://doi.org/10.37469/0507-3758-2018-64-5-570-577
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