Grebenkin, E. V., Kondrashova, L. M., Untesco, M., Epishkina, A. A., & Keshchyan, K. S. (2024). Adenosquamous Carcinoma in the Epithelial Inclusion Cyst of The Vagina — A Rare Clinical Case Report. Voprosy Onkologii, 70(1), 119–122. https://doi.org/10.37469/0507-3758-2024-70-1-119-122

Abstract

Squamous cell carcinoma is the most common malignant neoplasm of the vagina, accounting for 80 % to 90 % of cases, while adenocarcinoma occurs in up to 10 % of cases. However, there are literature records of isolated cases of adenosquamous carcinoma of this localization. Similar to the more studied adenosquamous carcinoma of the cervix, the development of this vaginal tumor is associated with oncogenic strains of the human papillomavirus. Epithelial inclusion cyst of the vagina is an extremely rare source of tumor growth. In 2012, the world's first case of squamous cell carcinoma in a squamous inclusion cyst of the vagina was reported.

Conclusion. Analysis of the available domestic and foreign literature allows us to state that the case we presented is probably the first published case of adenosquamous carcinoma in the inclusion epithelial cyst of the vagina.

https://doi.org/10.37469/0507-3758-2024-70-1-119-122

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