Research of topoisomerase IIa in conjunction with clinical and morphological parameters and proliferation (to identify argyrophilic proteins of nucleolar organizer regions and antigen ki-67) in lung adenocarcinoma
Vol. 69 No. 6 (2023), Articles
Vol. 69 No. 6 (2023)

Research of topoisomerase IIa in conjunction with clinical and morphological parameters and proliferation (to identify argyrophilic proteins of nucleolar organizer regions and antigen ki-67) in lung adenocarcinoma

Articles
https://doi.org/10.37469/0507-3758-2014-60-2-63-68
Published 15.12.2014
City Hospital, Kogalym
Altai Medical University
Altai branch of the N.N. Blokhin Russian Cancer Research Center
Altai branch of the N.N. Blokhin Russian Cancer Research Center
Altai branch of the N.N. Blokhin Russian Cancer Research Center
Research Institute of Regional Pathology and Pathomorphology
Research Institute of Regional Pathology and Pathomorphology
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PDF (Русский)

Keywords

Ki-67
topoisomerase ІІα
argyrophilic proteins of nucleolar organizer regions
lung adenocarcinoma

How to Cite

, , , , , , & . (2014). Research of topoisomerase IIa in conjunction with clinical and morphological parameters and proliferation (to identify argyrophilic proteins of nucleolar organizer regions and antigen ki-67) in lung adenocarcinoma. Voprosy Onkologii, 69(6), 63–68. https://doi.org/10.37469/0507-3758-2014-60-2-63-68
ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver

Abstract

Investigated topoisomerase ІІα (ТороІІα), argyrophilic proteins associated with nucleolar organizer regions (Ag-NOR) and antigen Ki-67 in lung adenocarcinoma. Defined tumor with low and high ТороІІа, Ag-NOR and Ki-67. ТороІІа had a relationship with clinical and morphological parameters (greatest dimension, tumor differentiation ) and proliferation markers (Ag-NOR, Ki-67) . Survival of patients with lung adenocarcinoma with low content of ТороІІα is better as compared with high content of ТороІІα. Survival of patients with lung adenocarcinoma depends on the mutual content of ТороІІα and clinical and morphological parameters (value T, greatest dimension, value N, stage, tumor differentiation), proliferation markers (Ag-NOR). ТороІІα content in lung adenocarcinoma is an independent prognostic factor. Mutual research of ТороІІα with clinical and morphological parameters and Ag-NOR has prognostic value in lung adenocarcinoma.
https://doi.org/10.37469/0507-3758-2014-60-2-63-68
##article.numberofdownloads## 22
##article.numberofviews## 65
PDF (Русский)

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