Markers of effectiveness of preoperative taxane-chemotherapy for locally advanced breast cancer
Vol. 70 No. 1 (2024), Articles
Vol. 70 No. 1 (2024)

Markers of effectiveness of preoperative taxane-chemotherapy for locally advanced breast cancer

Articles
https://doi.org/10.37469/0507-3758-2013-59-3-363-368
Published 15.12.2013
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
I.P.Pavlov State Medical University
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
N.N.Petrov Research Institute of Oncology
PDF (Русский)

Keywords

TOP2a

How to Cite

, , , , , , , , , , , , , , , , , & . (2013). Markers of effectiveness of preoperative taxane-chemotherapy for locally advanced breast cancer. Voprosy Onkologii, 70(1), 363–368. https://doi.org/10.37469/0507-3758-2013-59-3-363-368
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Abstract

The absolute sensitivity signs of breast cancer to the drug have not yet been developed. Data from clinical trials on the study of experimental laboratory predictive markers of chemosensitivity: TOP2a (topoisomerase 2-alpha), P-tubulin (subunit of dimeric protein tubulin), and BRCA1 (breast cancer 1) are contradictory and not numerous. Analysis of the results by the end of the clinical trial will allow examining the correlation between the effectiveness of preoperative taxane-chemotherapy and the level of experimental and standard molecular markers that is important for development of algorithm of treatment tactics for patients with locally advanced breast cancer.
https://doi.org/10.37469/0507-3758-2013-59-3-363-368
PDF (Русский)

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