Modern possibilities of first-line therapy for advanced renal cell carcinoma: resolution based on the expert council's findings
Vol. 69 No. 2 (2023), EXPERT OPINION
Vol. 69 No. 2 (2023)

Modern possibilities of first-line therapy for advanced renal cell carcinoma: resolution based on the expert council's findings

EXPERT OPINION
https://doi.org/10.37469/0507-3758-2023-69-2-316-321
Published 30.04.2023
Yulia Anzhiganova
КГБУЗ КККОД им.А.И.Крыжановского
https://orcid.org/0000-0002-8388-466X
Оlga Baklanova
Иркутский областной онкологический диспансер
https://orcid.org/0000-0002-2331-506X
Sergei Varlamov
Алтайский краевой онкологический диспансер
https://orcid.org/0000-0002-2002-3336
Vladislav Vodolazskiy
Омский областной клинический онкологический диспансер
https://orcid.org/0000-0002-6839-5411
Olga Zharkova
Камчатский краевой онкологический диспансер
https://orcid.org/0000-0001-8021-2051
Ruslan Zykov
КГБУЗ КККОД им. А.И.Крыжановского
https://orcid.org/0000-0003-1576-5930
Feodosiya Ivanova
Якутский республиканский онкологический диспансер
https://orcid.org/0000-0001-7661-1279
Evgeny Kopyltsov
Омский областной клинический онкологический диспансер
https://orcid.org/0000-0003-3165-9118
Olga Novikova
Краевой клинический Центр Онкологии Хабаровского края
https://orcid.org/0000-0002-0950-0648
Marina Skoraya
Новосибирский областной клинический онкологический диспансер
Evgeny Usynin
НИИ онкологии Томского национального исследовательского медицинского центра Российской академии наук
https://orcid.org/0000-0001-7127-0188
pdf (Русский)

Keywords

Advanced renal cell carcinoma
aRCC
Lenvatinib
pembrolizumab
combination therapy

How to Cite

Anzhiganova , Y., Baklanova О., Varlamov , S., Vodolazskiy , V., Zharkova , O., Zykov , R., Ivanova , F., Kopyltsov , E., Novikova, O., Skoraya , M., & Usynin , E. (2023). Modern possibilities of first-line therapy for advanced renal cell carcinoma: resolution based on the expert council’s findings. Voprosy Onkologii, 69(2), 316–321. https://doi.org/10.37469/0507-3758-2023-69-2-316-321
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Abstract

This article presents the findings of a regional expert council meeting on renal cell carcinoma (RCC) in Siberia and the Far East, held on May 20, 2022, in Novosibirsk. The meeting aimed to coordinate patient management tactics in systemic therapy for advanced RCC (aRCC), discuss clinical experience with immune-targeted regimens, and obtain expert opinions on the study of lenvatinib in combination with pembrolizumab for aRCC patients. The council discussed different approaches to treatment based on clinical guidelines and real world practice, the provision of modern first-line combination therapy options for patients in Siberia and the Far East, and the specific routing of this patient cohort. The agenda included identifying the ideal patient profile for combined immune-targeted therapy with lenvatinib and pembrolizumab, with emphasis on toxicity control. The meeting also addressed significant pharmacoeconomic issues and ways to tackle them.

https://doi.org/10.37469/0507-3758-2023-69-2-316-321
pdf (Русский)

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