Isolated pelvic perfusion in treatment for malignant tumors
PDF (Русский)

Keywords

isolated pelvic perfusion
recurrence of rectal cancer
recurrence of cervical cancer
balloon catheters

How to Cite

, , , , , , , , , , , , , & . (2016). Isolated pelvic perfusion in treatment for malignant tumors. Voprosy Onkologii, 62(3), 379–389. https://doi.org/10.37469/0507-3758-2016-62-3-379-389

Abstract

Rationale and feasibility of isolated pelvic perfusion (IPP) as a high-tech treatment modality for patients with pelvic malignancies was studied and analyzed based on the systematic review of the literature. Indications, techniques and regimens of IPP are reviewed. There is a focus on anticancer agents for IPP and methods of complete vascular isolation of the perfusated region. Data on the short- and long-term outcome of patients after IPP are presented. To the best of authors’ knowledge this is the first Russian article regarding application of IPP in oncology practice.
https://doi.org/10.37469/0507-3758-2016-62-3-379-389
PDF (Русский)

References

Бойко В.В., Криворотько И.В. 10-летний опыт применения комбинированных операций при местнораспрастраненном раке прямой кишки // Междунар. мед. журнал. - 2009. - №1. - С. 50-57.

Интервенционная радиология в онкологии / Гл. ред.: А.М. Гранов, М.И. Давыдов; ред.: П.Г. Таразов, Д.А. Гранов. - 2-е изд., доп. - СПб: Фолиант, 2013. - 545 с.

Киреева Г.С., Беляева О.А., Беспалов В.Г. и др. Нормотермическая и гипертермическая интраперитонеальная перфузионная химиотерапия диссеминированного рака яичника в эксперименте // Вестн. Эксперимент. и клин. хирургии. - 2015. - Т. 8, №2. - С. 235-242.

Майстренко Н.А., Хватов А.А., Учваткин Г.В., Сазонов А.А. Экзентерация малого таза в лечении местно-распространённых опухолей // Вестн. хирургии им. И.И. Грекова. - 2014. - №6. - С. 37-42.

Ahmed K., Zaidi S.F. Treating cancer with heat: hyperthermia as promising strategy to enhance apoptosis // J. Pak. Med. Assoc. - 2013. - Vol. 63. - P 504-508.

Aigner K.R., Kaevel K. Pelvic stopflow infusion (PSI) and hypoxic pelvic perfusion (HPP) with mitomycin and melphalan for recurrent rectal cancer // Reg. Cancer Treat. - 1994. - Vol. 7. - P. 6-11.

Alexander Jr.H.R., Fraker D.L., Bartlett D.L. et al. Analysis of Factors Influencing Outcome in Patients With In-Transit Malignant Melanoma Undergoing Isolated Limb Perfusion Using Modern Treatment Parameters // J. Clin. Oncol. - 2010. - Vol. 28. - P 114-118.

Austen W.G., Monaco A.P., Richardson G.S. et al. Treatment of malignant pelvic tumors by extracorporeal perfusion with chemotherapeutic agents // N. Engl. J. Med. - 1959. - Vol. 261. - P 1037-1045.

Begossi G., Belliveau J.F., Wanebo H.J. Pelvic perfusion for advanced colorectal cancers // Surg. Oncol. Clin. N. Am. - 2008. - Vol. 17. - P 825-842.

Bellone S., Pecorelli S., Cannon M.J., Santin A.D. Advances in dendritic-cell-based therapeutic vaccines for cervical cancer // Expert Rev. Anticancer Ther. - 2007. - Vol. 7. - P. 1473-1486.

Bonvalot S., Bonnay M., Drouard-Troalen L. et al. Presure-suit combined with pelvic stop-flow : a feasibility study in a bovine model // Eur. J. Surg. Oncol. - 2007. - Vol. 33. - P. 114-118.

Bonvalot S., de Baere T., Mendiboure J. et al. Hyperthermic pelvic perfusion with tumor necrosis factor-а for locally advanced cancers: encouraging results of a phase II study // Ann. Surg. - 2012. - Vol. 255. - P 281-286.

Bonvalot S., Muret J., Debaere T. et al. High response rates with isolated pelvic perfusion (IPP) with a pneumatic anti-shock garments (PASG) and low dose TNF-a for locally advanced pelvic sarcomas and carcinomas: a phase II unicenter trial // J. Clin. Oncol. 2008. - Vol. 26 (Suppl). - №10586.

Bonvalot S., Muret J., Debaere T. La perfusion pelvienne sous circulation extracorporelle dans les tumeurs pelviennes localement eґvolueґes [Pelvic perfusion for locally advanced tumors] // Bull. Cancer. - 2009. - Vol. 96. - P. 103-109.

Bosset J.F., Collette L., Calais G. et al. Chemotherapy with preoperative radiotherapy in rectal cancer // N. Engl. J. Med. - 2006. - Vol. 355. - P. 1114-1123.

Cavanagh D., Hovadhanakul P., Comas M.R. Regional chemotherapya comparison of pelvic perfusion and intra-arterial infusion in patients with advanced gynecologic cancer // Am. J. Obstet. Gynecol. - 1975. - Vol. 123. - P. 435-441.

Crowe P.J., Temple W.J., Lopez M.J., Ketcham A.S. Pelvic exenteration for advanced pelvic malignancy // Semin. Surg. Oncol. - 1999. - Vol. 17. - P. 152-160.

Dahl O. Interaction of hyperthermia and chemotherapy // Recent Res. Cancer Res. - 1988. - Vol. 107. - P. 157-169.

De Santis M., Ariosi P., Calo G.F. et al. Antineoplastic perfusion with percutaneous stop-flow control in the treatment of advanced pelvic malignant neoplasms // Radiol. Med. - 2000. - Vol. 100. - P. 56-61.

Guadagni S. Loco-regional perfusions (stop-flow techniques): state of art and future // J. Exp. Clin. Cancer Res. - 2003. - Vol. 22. - P 119-122.

Guadagni S., Aigner K.R., Palumbo G. et al. Pharmacokinetics of mitomycin C in pelvic stop ow infusion and hypoxic pelvic perfusion with and without hemo ltration: a pilot study of patients with recurrent unresectable rectal cancer // J. Clin. Pharmacol. - 1998. - Vol. 38. - P. 936-944.

Guadagni S., Clementi M., Valenti M. et al. Hypoxic abdominal stop-flow perfusion in the treatment of advanced pancreatic cancer: a phase II evaluation/trial // Eur. J. Surg. Oncol. - 2007. - Vol. 33. - P. 72-78.

Guadagni S., Fiorentini G., Palumbo G. et al. Hypoxic pelvic perfusion with mitomycin C using a simplified balloon-occlusion technique in the treatment of patients with unresectable locally recurrent rectal cancer // Arch. Surg. - 2001. - Vol. 136. - P 105-112.

Guadagni S., Kanavos E., Schietroma M. et al. Selected hypoxic stop-flow perfusions: indication and limits // Tumori. - 2006. - Vol. 92. - P. 402-406.

Gutman M., Abu-Abid S., Sorkine P. et al. Regional perfusion with hemofiltration (chemofiltration) for the treatment of patients with regionally advanced cancer // Cancer. -1996. - Vol. 78. - P 1125-1130.

Hamana S., Motoyama S., Takeuchi S. et al. Super highdose intraarterial cisplatin infusion under percutaneous pelvic perfusion with extracorporeal chemo ltration for advanced uterine cervical carcinoma. I. Analysis for pharmacokinetics, tumor response, and toxicity of platinum // Am. J. Clin. Oncol. - 2001. - Vol. 24. - P. 241-246.

Hayes A.J. Isolated limb perfusion with melphalan and tumor necrosis factor alpha for advanced melanoma and soft-tissue sarcoma // Ann. Surg. Oncol. - 2007. - Vol. 14. - P 230-238.

Hurley J.D., Wall T., Worman L.W. et al. Experiences with pelvic perfusion for carcinoma // Arch. Surg. - 1961. -Vol. 83. - P 127-135.

Iaffaioli R.V., Facchini G., Tortoriello A. et al. Stop flow in abdominal and pelvic relapses // Front. Biosci. - 2006. -Vol. 11. - P 1284-1288.

Klein E.S., Ben-Ari G.Y., Papa M.Z. et al. Vascular complications of total abdominal perfusion and aortic stop-flow infusion // J. Surg. Oncol. - 1996. - Vol. 61. - P. 17-19.

Klopp C.T. Regional intra-arterial nitrogen mustard as an adjunct to radiation therapy // Am. J. Roentgenol. Radium Ther. Nucl. Med. - 1953. - Vol. 70. - P 1005-1114.

Kocaoglu H., Yerdel M.A., Cetin R. et al. Treatment of non-resectable pelvic malignancies by isolated pelvic perfusion. A preliminary study // Eur. J. Surg. Oncol. - 1995. - Vol. 21. - P. 535-540.

Krakoff I.H., Sullivan R.D. Intra-arterial nitrogen mustard in the treatment of pelvic cancer // Ann. Intern. Med. -1958. - Vol. 48. - P 839-850.

Kuemmerle A., Decosterd L.A., Buclin T. et al. A phase I pharmacokinetic study of hypoxic abdominal stop-flow perfusion with gemcitabine in patients with advanced pancreatic cancer and refractory malignant ascites // Cancer Chemother. Pharmacol. - 2009. - Vol. 63. - P 331-341.

Lathrop J.C., Leone L.A., Soderberg C.H. Jr. et al. Perfusion chemotherapy for gynecological malignancy // Trans. N. Engl. Obstet. Gynecol. Soc. - 1968. - Vol. 17. - P. 47-56.

Lawrence W. Jr., Clarkson B., Kim M. et al. Regional perfusion of pelvis and abdomen by an indirect technique // Cancer. - 1963. - Vol. 16. - P. 567-582.

Lawrence W. Jr., Kuehn P., Mori S. et al. Regional perfusion of the pelvis: consideration of the ‘‘leakage’’ problem // Surgery. - 1961. - Vol. 50. - P. 248-259.

Leitao M.M., Chi D.S. Recurrent cervical cancer // Curr. Treat. Options Oncol. - 2002. - Vol. 3. - P 105-111.

Lin D., Wang C.H., Yu C.T. et al. Effect of endogenous nitric oxide on hyperoxia and tumor necrosis factor-alpha-induced leukosequestration and proinflammatory cytokine release in rat airways // Crit. Care Med. - 2003. - Vol. 31, №2. - P. 508-516.

Lorenz M., Heinrich S., Staib-Sebler E. et al. Regional chemotherapy in the treatment of advanced pancreatic cancer - is it relevant? // Eur. J. Cancer. - 2000. - Vol. 36. - P. 957-965.

Lorenz M., Petrowsky H., Heinrich S. et al. No benet of isolated hypoxic perfusion with mitomycin C in patients with advanced pancreatic cancer // Eur. J. Surg. Oncol. - 1998. - Vol. 24. - P 542-547.

Meyer F., Gebauer T., Grote R. et al. Results of regional chemotherapy using the aortic stop-flow technique in advanced pancreatic carcinoma // Surg. Today. - 2006. -Vol. 36. - P. 155-161.

Meyer F., Ridwelski K., Bebauer T. et al. Pharmacokinetics of the antineoplastic drug mitomycin C in regional chemotherapy using the aortic stop- ow technique in advanced pancreatic carcinoma // Chemotherapy. - 2005. - Vol. 51. - P. 1-8.

Mirnezami A.H., Sagar P.M., Kavanagh D. et al. Clinical algorithms for the surgical management of locally recurrent rectal cancer // Dis. Colon Rectum. - 2010. - Vol. 53. - P. 1248-1257.

Moen I., Oyan A.M., Kalland K.H. et al. Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model // PLoS One. - 2009. - Vol. 4, №7. - P 6381.

Moen I., Tronstad K.J., Kolmannskog O. et al. Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma // BMC Cancer. - 2009. - Vol. 9. - P 446.

Muchmore J.H., Krementz E.T., Carter R.D. et al. Treatment of abdominal malignant neoplasms using regional chemotherapy with hemofiltration // Arch. Surg. - 1991. - Vol. 126. - P. 1390-1396.

Muller H., Aigner K.R., Walther H. Isolated pelvic perfusion for nonresectable pelvic tumors. A pilot study // Reg. Cancer Treat. - 1989. - Vol. 2. - P 92-97.

Murata S., Onozawa S., Kim C. et al. Negative-balance isolated pelvic perfusion in patients with incurable symptomatic rectal cancer: results and drug dose correlation to adverse events // Acta Radiol. - 2014. -Vol. 55, №7. - Р 793-801

Murata S., Onozawa S., Oda T. et al. Pharmacological advantages of negative-balance isolated pelvic perfusion: achievement of intensive exposure of the pelvis to platinum without systemic leakage // Radiology. - 2012. - Vol. 262. - P. 503-510.

Murata S., Tajima H., Abe Y. et al. Changes in pelvic and systemic platinum concentrations during negativebalance isolated pelvic perfusion: correlation between platinum concentration and method of administration in a pig model // J. Cancer Res. Clin. Oncol. - 2007. - Vol. 133. - P 417-422.

Pilati P., Mocellin S., Miotto D. et al. Stop-flow technique for loco-regional delivery of antiblastic agents: literature review and personal experience // Eur. J. Surg. Oncol. 2001. - Vol. 28. - P. 544-553.

Pohlen U., Rieger H., Kunick-Pohlen S. et al. Phase II study of regional chemotherapy using the hypoxic abdominal perfusion technique in advanced abdominal carcinoma. 5-FU pharmacokinetics, complications and outcome // Anticancer Res. - 2007. - Vol. 27. - P. 667-674.

Raa A., Stansberg C., Steen V.M. et al. Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors // BMC Cancer. - 2007. - Vol. 7. - P. 23

Roberts N.J., Zhou S., Diaz L.A. Jr., Holdhoff1 M. Systemic use of tumor necrosis factor alpha as an anticancer agent // Oncotarget. - 2011. - Vol. 2. - P. 739-751.

Roversi R., Ricci S., Rossi G. et al. Results of ow-controlled antiblastic perfusions (stop- ow technique) carried out with percutaneous technique: 30-month experience // Radiol. Med (Torino). - 1997. - Vol. 93. - P. 732-738.

Ryan R.F. Dosage of chemotherapeutic agents for use with perfusion techniques // Cancer Chemother. Rep. -1960. - Vol. 10. - P. 47-51.

Ryan R.G., Schramel R.H., Creech O. Jr. Value of perfusion in pelvic surgery // Dis. Colon Rectum. - 1963. - Vol. 6. - P. 297-300.

Sartorelli A.C. Therapeutic attack of hypoxic cells of solid tumors: Presidential address // Cancer Res. - 1988. -Vol. 48. - P. 775-778.

Sebag-Monteore D., Stephens R.J., Steele R. et al. Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial // Lancet. - 2009. - Vol. 373. - P 811-820.

Shingleton W.W., Parker R.T., Mahaley S. Abdominal perfusion for cancer chemotherapy with hypothermia and hyperthermia // Surgery. - 1961. - Vol. 50. - P 260-265.

Stehlin J.S. Jr., Lee Clark R., White E.C. et al. Regional chemotherapy for cancer: experiences with 116 perfusions // Ann. Surg. - 1960. - Vol. 151. - P. 605-619.

Strawitz J.G., Wolferth C.C. Jr., Howard J.M. et al. Treatment of advanced cancer by isolation perfusion // Arch. Surg. - 1965. - Vol. 91. - P 678-683.

Strocchi E., Iaffaioli R.V., Facchini G. et al. Stop-flow tecnique for loco-regional delivery of high dose chemotherapy in the treatment of advanced pelvic cancers // EJSO. - 2004. - Vol. 30. - P. 663-670.

Stuhr L.E., Raa A., Oyan A.M. et al. Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats // J. Neurooncol. - 2007. - Vol. 85, №2. - P. 191-192.

Teicher B.A., Lazo J.S., Sartorelli A.C. Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells // Cancer Res. -1981. - Vol. 41. - P 73-81.

Turk P.S., Belliveau J.F., Darnowsky J.W. et al. Isolated pelvic perfusion for unrectable cancer using a balloon occlusion technique // Arch. Surg. - 1993. - Vol. 128. - P. 533-539.

Uzan C., Goere D., Dumont F. et al. Isolated pelvic perfusion in irradiated unresectable recurrence of pelvic tumor: preliminary outcome and ongoing study // J. Visc. Surg. - 2014. - Vol. 151. - P. 11-15.

Vaglini M., Cascinelli F., Chiti A. et al. Isolated pelvic perfusion for the treatment of unresectable primary or recurrent rectal cancer // Tumori. - 1996. - Vol. 82. - P. 459-462.

Van Horssen R., Ten Hagen T.L., Eggermont A.M. TNF- in Cancer Treatment: Molecular Insights, Antitumor Effects, and Clinical Utility // The Oncologist. - 2006. - Vol. 11. - P. 397-408.

Van IJken M.G.A., van Etten B., Guetens G. et al. Balloon catheter hypoxic abdominal perfusion with mitomycin C and melphalan for locally advanced pancreatic cancer: a phase I-II trial // Eur. J. Surg. Oncol. - 2004. - Vol. 30. - P 671-680.

Van IJken M.G.A., van Etten B., Guetens G. et al. Balloon catheter hypoxic pelvic perfusion with mitomycin C and melphalan for locally advanced tumours in the pelvic region: a phase I-II trial // Eur. J. Surg. Oncol. - 2005. -Vol. 31. - P 897-904.

Varrassi G., Guadagni S., Ciccozzi A. et al. Hemodynamic variations during thoracic and abdominal stop- ow regional chemotherapy // Eur. J. Surg. Oncol. - 2004. - Vol. 30. - P. 377-383.

Wanebo H.J., Belliveau J., Begossi G., Levy A. Isolated chemotherapeutic perfusion of the pelvis for advanced rectal cancer // Colorectal Dis. - 2003. - Vol. 5 - P. 508-514.

Wanebo H.J., Chung M.A., Levy A.I. et al. Preoperative therapy for advanced pelvic malignancy by isolated pelvic perfusion with the balloo-occlusion technique // Ann. Surg. Oncol. - 1996. - Vol. 3. - P 295-303.

Wanebo H.J., DiSiena M., Begossi G. et al. Isolated chemotherapeutic perfusion of pelvis as neoadjuvant or palliative therapy for advanced cancer of the rectum // Ann. Surg. Oncol. - 2008. - Vol. 15. - P. 1107-1116.

Watkins E. Jr., Hering A.C., Luna R. et al. The use of intravascular balloon catheters for isolation of the pelvic vascular bed during pump-oxygenator perfusion of cancer chemotherapeutic agents // Surg. Gynecol. Obstet. -1960. - Vol. 111. - P. 464-468.

Wile A., Smolin M. Hypertermic pelvic isolation-perfusion in the treatment of refractory pelvic cancer // Arch. Surg. - 1987. - Vol. 122. - P. 1321-1325.

Yokoyama I., Yamanaka N., Kato N. et al. Pelvic perfusion hyperthermia for advanced pelvic malignancies // Jpn. J. Surg. - 1985. - Vol. 15. - P 49-54.

Yun H.R., Lee L.J., Park J.H. et al. Local recurrence after curative resection in patients with colon and rectal cancers // Int. J. Colorectal Dis. - 2008. - Vol. 23. - P. 1081-1087.

Zanon C., Goss M., Nicola F. et al. Limits of aortic stop flow infusion chemotherapy in the treatment of advanced cancer // Panminerva Med. - 2001. - Vol. 43. - P. 243-248.

All the Copyright statements for authors are present in the standart Publishing Agreement (Public Offer) to Publish an Article in an Academic Periodical 'Problems in oncology' ...