How to Cite
Abstract
Breast cancer is the most common malignant tumor in women. Simultaneous reconstructive interventions using endoprostheses account for approximately 70-75 % of all reconstructions in modern reconstructive plastic surgery. The frequency of animation deformity reaches 76 % in subpectoral reconstruction. At the same time, women feel discomfort in everyday life, the phenomenon of chronic postoperative pain. The options for correcting the animation deformity usually involve repeated surgical interventions, which do not guarantee reliable correction of the animation deformity, and only the replacement of the implant with a new one in a prepectoral position, which is not always possible, radically solves the problem. The aim of this review is to summarize the functional and aesthetic results of botulinum toxin type A (BTA) injections in the area of the reconstructed breast, to analyze the methodology and safety of administration in the treatment of animation deformity. A review of the literature has shown that the use of botulinum toxin type A is a minimally invasive, effective, but reversible alternative to surgical treatment options. In the vast majority of cases, the injection was given in the pectoralis major muscle (including intraoperatively) or in the latissimus dorsi muscle, more commonly at a dose of 100 IU per zone, although the safety of increasing the dose to 250 IU has been demonstrated. No local or systemic adverse reactions were reported. Due to the reversibility of the effect, it is recommended that the injections be repeated at intervals of 3-4 months. The subjective muscle relaxant effect occurred at least 3 days after the first BTA injection and coincided with the onset of pain relief. In addition, the use of BTA significantly reduced the use of narcotic analgesics from 7-14 days post-operatively. Due to the limited number of studies on this topic, further observation and research is needed on the issues discussed in the review.
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