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Preliminary results of complex treatment of 58 patients with I-IIIC breast cancer (T1-4N0-3M0) who underwent radical mastectomy with reconstruction of the breast in its various variants and conformal radiotherapy in adjuvant mode to the pectoral region and regional lymph drainage are presented in the article. A low incidence of complications from the reconstructed breast was noted: two (7 %) cases of implant removal due to pronounced capsular contracture and in connection with infection of the implant bed. At the time of observation of patients from 11.5 to 158.9 months, median 18.6 months, in 3 (5 %) patients clinically significant radiation pulmonitis was detected. The overall two-year survival was 97 % and progression-free survival was 90 %. In 6 (10 %) patients distant me-tastases were detected, in 1 (2 %) - recurrence of the disease in the area of postoperative scar. Thus reconstructive-plastic surgery can be an integral part of complex anti-tumor treatment including radiotherapy with direct indications to it in full volume and dose.References
Давыдов М. И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ - М., 2014.
Состояние онкологической помощи населению России в 2015 году / под редакцией А.Д. Каприна, В.В. Старинского, Г.В. Петровой. - М., 2016.
Ascherman J.A., Hanasono M.M., Newman M.I. et al. Implant reconstruction in breast cancer patients treated with radiation therapy // Plast. Reconstr. Surg. - 2006. -Vol. 117. - P 359-365.
Behranwala K.A., Dua R.S., Ross G.M. et al. The influence of radiotherapy on capsule formation and aesthetic outcome after immediate breast reconstruction using biodimensional anatomical expander implants // JPRAS. - 2006. - Vol. 59. - P. 1043-1051.
Carnevale A., Scaringi C. et al. Radiation therapy after breast reconstruction: outcomes, complications and patient satisfaction // Radiol. Med. - 2013. - Vol. 118 (7). - P. 1240-50.
Coates A.S., Winer E.P., Goldhirschet A. et al. Tailoring therapies - improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015 // Ann. Oncol. - 2015. - Vol. 26 (9).
Daisuke Ota, Atsushi Fukuuchi, Yoshiko Iwahira et al. Clinical Outcome of Reconstruction With Tissue Expanders for Patients With Breast Cancer and Mastectomy // Clinical Breast Cancer. - 2014. - Vol. 14. - № 5. - P. 339-345.
Evidence-Based Clinical Practice Guideline: Breast Reconstruction with Expanders and Implants. - American Society of Plastic Surgeons, 2013.
Harmeling J. Xavier, Casimir A.E. Kouwenberg, Eveline Bijlard et al. The effect of immediate breast reconstruction on the timing of adjuvant chemotherapy: a systematic review // Breast Cancer Res Treat. - 2015. - Vol. 153 (2). - P. 241-251.
Ho A., Cordeiro P., Disa J. et al. Long-Term Outcomes in Breast Cancer Patients Undergoing Immediate 2-Stage Expander/Implant Reconstruction and Postmastectomy Radiation // Cancer. - 2012. - Vol. 118. - P. 2552-2559.
Monrigal E., Dauplat J., Gimbergues P. et al. Mastectomy with immediate breast reconstruction after neoadjuvant chemotherapy and radiation therapy. A new option for patients with operable invasive breast cancer. Results of a 20 years single institution study // Eur. J. Surg. Oncol. - 2011. - Vol. 37(10). - P. 864-870.
NCCN Guideline for breast cancer. Version 01.2016.
Warren Matthew Rozen, Mark W. Ashton, G. Ian Taylor. Defining the Role for Autologous Breast Reconstruction After Mastectomy: Social and Oncologic Implications // Clinical Breast Cancer. - 2008. - Vol. 8. - № 2. - P. 134-142.
Tsoi B., Ziolkowski N.I., Thoma A. et al. Systematic Review on the Patient-Reported Outcomes of Tissue-Expander/ Implant vs Autologous Abdominal Tissue Breast Reconstruction in Postmastectomy Breast Cancer Patients // J. Am. Coll. Surg. - 2014. - Vol. 218. - Issue 5. -P. 1038-1048.
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