MAMMOGRAPHY AND MAMMOSCINTIGRAPHY WITH 99M TC-MIBI IN THE DIAGNOSIS OF MULTICENTRIC BREAST CANCER
Vol. 63 No. 6 (2017), ORIGINAL ARTICLES. A. PROTOCOLS OF CLINICAL RESEARCH
Vol. 63 No. 6 (2017)

MAMMOGRAPHY AND MAMMOSCINTIGRAPHY WITH 99M TC-MIBI IN THE DIAGNOSIS OF MULTICENTRIC BREAST CANCER

ORIGINAL ARTICLES. A. PROTOCOLS OF CLINICAL RESEARCH
https://doi.org/10.37469/0507-3758-2017-63-6-876-881
Published 01.06.2017
Antonina Chernaya
N.N. Petrov National Medical Research Center of Oncology
Tatyana Shumakova
I.P. Pavlov First St. Petersburg State Medical University
Yekaterina Busko
N.N. Petrov National Medical Research Center of Oncology
Nadezhda Popova
N.N. Petrov National Medical Research Center of Oncology
Anna Artemeva
N.N. Petrov National Medical Research Center of Oncology
Petr Krivorotko
N.N. Petrov National Medical Research Center of Oncology, I.I. Mechnikov North-West State Medical University
Pavel Krzhivitskiy
N.N. Petrov National Medical Research Center of Oncology
Sergey Novikov
N.N. Petrov National Medical Research Center of Oncology
Sergey Kanaev
N.N. Petrov National Medical Research Center of Oncology
Viktoriya Bashlyk
N.N. Petrov National Medical Research Center of Oncology
PDF (Русский)

Keywords

BREAST CANCER
MAMMOGRAPHY
MULTICENTRIC BREAST CANCER
MAMMOSCINTIGRAPHY

How to Cite

Chernaya, A., Shumakova, T., Busko, Y., Popova, N., Artemeva, A., Krivorotko, P., Krzhivitskiy, P., Novikov, S., Kanaev, S., & Bashlyk, V. (2017). MAMMOGRAPHY AND MAMMOSCINTIGRAPHY WITH 99M TC-MIBI IN THE DIAGNOSIS OF MULTICENTRIC BREAST CANCER. Voprosy Onkologii, 63(6), 876–881. https://doi.org/10.37469/0507-3758-2017-63-6-876-881
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Abstract

Objective: To compare diagnostic capability of mammography and mammoscintigraphy with 99mTc-methoxyisobutylisonitrile (MIBI) in diagnostic of multicentric breast cancer. Material and Methods: We respectively analyzed 437 consecutive women with suspected breast cancer between 2014 to 2016. All of them underwent mammography and mammoscintigraphy. Craniocaudal and mediolateral oblique images were obtained. Mammoscintigraphy was performed 15-20 min. after intravenous injection 740 MBq of 99mTc-methoxyisobutylisonitrile (MIBI). Final interpretation of the data was done according to histological examination. Results: Breast cancer was detect in 367(84%) of patients. Most of them 320(87%) had single node breast cancer and 47(13%) - multicentric breast cancer. Sensitivity, specificity and accuracy in diagnostic of multicentric breast cancer were 40,4%, 95,3%, 88% for mammography and 83%, 98%, 96% for mammoscintigraphy respectively. The combination of these methods allowed significantly increase sensitivity of breast cancer detection up to 93,6%. Specificity was 93,4%.
https://doi.org/10.37469/0507-3758-2017-63-6-876-881
PDF (Русский)

References

Канаев C.В., Новиков С.Н., Семиглазов В.Ф. и соавт. Возможности раннего выявления новообразований рака молочной железы с помощью ультразвуковых и радионуклидных методов диагностики // Вопросы онкологии. - 2011. - Т. 57. - № 5. - С. 622-626.

Канаев С.В., Новиков С.К, Криворотько П.В. и др. Методические аспекты радионуклидной диагностики рака молочной железы с помощью 99 МТС-технетрила // Вопросы онкологии. - 2012. - Т. 58. - № 6. - С. 768-772.

Канаев С.В., Новиков С.Н., Зотова О.В. и др. Перспективы использования методов ядерной медицины у больных раком молочной железы // Вопросы онкологии. - 2009. - Т. 55. - № 6. - С. 661-670.

Криворотько П.В. Диагностическая значимость маммографии и маммосцинтиграфии при мультицентрич-ном раке молочной железы // Вопросы онкологии. - 2013. - Т. 59. - № 1. - C. 59-64.

Семиглазов В.Ф, Семиглазов В.В, Клецель А.Е. Неинвазивные и инвазивные опухоли молочной железы. - Санкт-Петербург, 2006. - С. 69-84.

Тицкая А.А., Чернов В.И., Синилкин И.Г. и др. Стандартизованные методики радионуклидной диагностики / Маммосцинтиграфия Библиотека практического врача. - ООО «НТЦ Амплитуда» Москва, Зеленоград, 2014. - 32 с.

Тицкая А.А., Чернов В.И., Слонимская Е.М. и др. Сравнение результатов маммосцинтиграфии с 99mTc-Технетрилом в планарном и томографическом режимах // Медицинская радиология и радиационная безопасность. - 2008. - № 5. - С.51-59.

Чёрная А.В., Канаев С.В., Новиков С.Н. и др. Диагностическая значимость маммографии и маммосцинтигра-фии с 99м Тс-MIBI при выявлении минимального рака молочной железы // Вопросы онкологии. - 2017. - Т. 63. - № 2. - C. 274-280.

Berg W.A., Gilbreath P.L. Multicentric and multifocal cancer: whole-breast US in preoperative evaluation // Radiology. - 2000. - Vol. 214. - P. 59-66.

Berg W.A., Gutierrez L. NessAiver M.S. et al. Diagnostic accuracy of mammography, clinical examination, US, and MR imaging in preoperative assessment of breast cancer // Radiology. - 2004. - Vol. 233. - P. 830-849.

Chen G., Ouyang Z., Wang F. et al. Evaluation of Tc-99m-3PRGD2 Integrin Receptor Imaging in the Differential Diagnosis of Breast Lesions and Comparison With Mammography //.Cancer Invest. - 2017. - Vol. 35 (2). - P. 108-115.

Even-Sapir T., Golan O., Menes T. et al. Breast Imaging Utilizing Dedicated Gamma Camera and 99mTc-MIBI: Experience at the Tel Aviv Medical Center and Review of the Literature Breast Imaging // Q. J. Nucl. Med. Mol. Imaging. - 2016. - Vol. 46. - P. 286-293.

Green VL. Mammographic Breast Density and Breast Cancer Risk: Implications of the Breast Density Legislation for Health Care Practitioners.// Clin. Obstet Gynecol. - 2016. - Vol. 59(2). - P. 419-438.

Khalkhali I., Mena I., Diggles I. Review of imaging techniques for the diagnosis of breast cancer: a new role of prone scintimammography using technetium-99m sestambi // Eur. J. Nucl. Med. - 1994. - Vol. 21. - P. 357-362.

Spanu A.,Chessa F. et al. Scintimammography with high resolution dedicated breast camera and mammography in multifocal, multicentric and bilateral breast cancer detection// Q. J. Nucl. Med. Mol. Imaging. - 2009. - Vol. 53. - P. 133-143.

Tan H., Zhang H., Yang W. et al. Breast-specific gamma imaging with Tc-99m-sestamibi in the diagnosis of breast cancer and its semiquantitative index correlation with tumor biologic markers, subtypes, and clinicopathologic characteristics // Nucl. Med. Commun. - 2016. - Vol. 37(8). - P. 792-799.

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