THE ADVANTAGES OF HYBRID SCINTIGRAPHY IN SENTINEL NODE MAPPING IN PATIENTS WITH BREAST CANCER
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Keywords

BREAST CANCER
LYMPHOSCINTIGRAPHY
SENTINEL LYMPH NODES
SPECT-CT

How to Cite

Solodkiy, V., Fomin, D., Khodorovich, O., Borisova, O., Lyugay, O., Semakina, T., & Pyatnitskiy, I. (2019). THE ADVANTAGES OF HYBRID SCINTIGRAPHY IN SENTINEL NODE MAPPING IN PATIENTS WITH BREAST CANCER. Voprosy Onkologii, 65(2), 238–242. https://doi.org/10.37469/0507-3758-2019-65-2-238-242

Abstract

We performed comparative analysis of the efficiency of planar scintigraphy and SPECT-CT in the localization of sentinel lymph nodes (SLN) in the early stages of breast cancer in 50 patients. The true amount of SLN by lymphoscintigraphy was detected in 48% of observations, clear visualization was achieved in 78% of cases. There was no significant correlation between the efficiency of the planar study and the body mass index of the patients. The SPECT-CT analysis of regional lymphatic drainage of the mammary gland allowed to determine both the exact localization and the number of SLN in all patients included in the study. Comparison of SLN size and structure with histology results revealed no reliable association between CT anatomy and the presence of metastases in the lymph nodes.
https://doi.org/10.37469/0507-3758-2019-65-2-238-242
PDF (Русский)

References

Alex J.C., Krag D.N. Gamma-probe guided localization of lymph nodes // surg oncol. - 1993. - Vol. 2(3). - P 137-143.

Canavese G., Bruzzi P., Catturich A. et al. sentinel lymph node biopsy versus axillary dissection in node-negative early-stage breast cancer: 15-year follow-up update of a randomized clinical trial // Ann. surg. oncol. - 2016. - Vol. 23(8). - P 2494-2500.

Cabanas R.M. An approach for the treatment of penile carcinoma // Cancer. - 1977. - Vol. 39(2). - P. 456-466.

Jimenez-Heffernan A., Ellmann A., Sado H. et al. Results of a prospective multicenter international atomic energy agency sentinel node trial on the value of sPECT/CT over planar imaging in various malignancies // J. NucI. Med. - 2015. - Vol. 56(9). - P 1338-1344.

Kraft O., Havel M. Sentinel lymph node identification in breast cancer-comparison of planar scintigraphy and sPECT/CT // Open Nucl. Med. J. - 2012. - № 4. - P 5-13.

Latosinsky S., Dabbs K., Moffat F. Evidence-Based Reviews in surgery Group. Canadian Association of General surgeons and American College of surgeons Evidence-Based Reviews in surgery. 27. Quality-of-life outcomes with sentinel node biopsy versus standard axillary treatment in patients with operable breast cancer. Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer: the ALMANAC Trial // Can J. surg. - 2008. - № 51. - P 483.

Lucci A., McCall L.M., Beitsch P.D. et al. surgical complications associated with sentinel lymph node dissection (sLND) plus axillary lymph node dissection compared with sLND alone in the American College of surgeons oncology Group Trial Z0011 // J. Clin. Oncol. - 2007. - Vol. 25. - P 3657.

Mansel R.E., Fallowfield L., Kissin M. et al. Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer: the ALMANAC Trial // J. Natl. Cancer Inst - 2006. - Vol. 98. - № 9. - P. 599-609.

Olmos R.V., Rietbergen D.D., Vidal-Sicart S. et al. Contribution of sPECT/CT imaging to radioguided sentinel lymph node biopsy in breast cancer, melanoma, and other solid cancers: from "open and see" to "see and open" // Q J. Nucl. Med. Mol. Imaging. - 2014. - № 58. - P. 127-139.

Siddique M., Nawaz M.K., Bashir H. The Usefulness of SPECT/CT in Sentinel Node Mapping of Early Stage Breast Cancer Patients Showing Negative or Equivocal Findings on Planar Scintigraphy // Asia Ocean J. Nucl. Med. Biol. - 2018. - Vol. 6(2). - P. 80-89.

Van der Ploeg I.M., Valdes Olmos R.A., Nieweg O.E. et al. The additional value of SPETCT/TC in lymphatic mapping in breast cancer and melanoma // J. Nucl. Med. - 2007. -Vol. 48(11). - P 1756-1760.

Verheuvel N.C., Voogd A.C., Tjan-Heijnen V.C. et al. Different outcome in node-positive breast cancer patients found by axillary ultrasound or sentinel node procedure // Breast Cancer Res Treat. 2017. - Vol. 165 (3) - P 555-563.

Vidal-sicart S., Valdes Olmos R. Sentinel node mapping for breast cancer: current situation // J. Oncol. 2012. - Vol. 2012 - P. 341-361.

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