摘要
介绍
胰腺囊性肿瘤的鉴别诊断由于其结构特征仍然是一个复杂的挑战。胰腺液作为一种高度特异性的介质,包含细胞成分和潜在的分子标志物,因而备受关注。本研究介绍了一种新型的主动十二指肠吸取液体活检(DALB)方法,可用于收集胰腺液和胆汁的混合物。
研究目的
评估原始 DALB 技术与标准诊断方法相结合的有效性。
材料与方法
对接受了一系列标准诊断程序但未能获得明确诊断的患者进行 DALB。收集的吸取液进行细胞学分析,并测量癌胚抗原(CEA)水平。
研究结果
本研究共纳入 6 例不同类型的胰腺囊性肿瘤患者,结果表明 DALB 可与标准验证程序结合使用。获取的 CEA 水平和细胞学检测结果使得准确诊断成为可能,并指导了合理的治疗调整。
结论
本研究经验表明,DALB 技术安全有效,可应用于不同的医疗环境(门诊或住院),并有潜力提高胰腺癌的早期诊断率
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