主動抽吸液體切片在胰臟腫瘤診斷的應用
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关键词

胰腺癌,囊性病变,急性胰腺炎,胰腺液。

How to Cite

Кашинцев, А. А., 科哈年科尼., 帕維萊特康., Соловьев, И. А., 魯薩諾夫德., 瓦維洛娃奧., 拉迪諾夫尤., 瓜類米., 阿加波夫米., 珀利帕斯尤., 古利亞耶夫尤., Моргошия, Т. Ш., 馬戈梅多娃法., 索洛維奧娃柳., 納德耶娃阿., Боровикова, А. С., Лаптев, К. В., Лемешев, А. В., & 普魯茨基維. (2025). 主動抽吸液體切片在胰臟腫瘤診斷的應用. VOPROSY ONKOLOGII, 71(6), OF–2340. https://doi.org/10.37469/0507-3758-2025-71-6-OF-2340

摘要

介绍
胰腺囊性肿瘤的鉴别诊断由于其结构特征仍然是一个复杂的挑战。胰腺液作为一种高度特异性的介质,包含细胞成分和潜在的分子标志物,因而备受关注。本研究介绍了一种新型的主动十二指肠吸取液体活检(DALB)方法,可用于收集胰腺液和胆汁的混合物。

研究目的
评估原始 DALB 技术与标准诊断方法相结合的有效性。

材料与方法
对接受了一系列标准诊断程序但未能获得明确诊断的患者进行 DALB。收集的吸取液进行细胞学分析,并测量癌胚抗原(CEA)水平。

研究结果
本研究共纳入 6 例不同类型的胰腺囊性肿瘤患者,结果表明 DALB 可与标准验证程序结合使用。获取的 CEA 水平和细胞学检测结果使得准确诊断成为可能,并指导了合理的治疗调整。

结论
本研究经验表明,DALB 技术安全有效,可应用于不同的医疗环境(门诊或住院),并有潜力提高胰腺癌的早期诊断率

https://doi.org/10.37469/0507-3758-2025-71-6-OF-2340
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