MESENCHYMAL CHONDROSARCOMA OF THE HEAD AND NECK. AN OVERVIEW OF THE FEATURES, PROGNOSTIC FACTORS AND DIRECTIONS OF THE SEARCH FOR TREATMENT STRATEGIES. CLINICAL CASE
PDF (Русский)

Keywords

MESENCHYMAL CHONDROSARCOMA
HEAD AND NECK TUMORS

How to Cite

Baryshev, V., Sevryukov, F., Andreev, V., Kondrashova, L., Kapinus, V., Polkin, V., Pankratov, V., Akki, E., Baryshev, K., Kaprin, A., & Ivanov, S. (2020). MESENCHYMAL CHONDROSARCOMA OF THE HEAD AND NECK. AN OVERVIEW OF THE FEATURES, PROGNOSTIC FACTORS AND DIRECTIONS OF THE SEARCH FOR TREATMENT STRATEGIES. CLINICAL CASE. Voprosy Onkologii, 66(4), 420–424. https://doi.org/10.37469/0507-3758-2020-66-4-420-424

Abstract

Mesenchymal chondrosarcoma is a rare highly differentiated malignant tumor with a characteristic histological structure, which affects bones or soft tissues and has a high potential for local recurrence. The small number of observations of mesenchymal chondrosarcoma in the head and neck region causes the episodic nature of studies of this problem, and the treatment and diagnostic tactic remains controversial. The article presents the results of the most extensive and systematic studies, which show that the main method of treatment for this category of patients is surgical. Neoadjuvant or adjuvant chemotherapy tends to improve overall survival. Radiation therapy is used as adjuvant treatment. The work provides a clinical case of a long lifetime of a patient with local recurrence of the disease in the absence of regional, distant metastasis and the use of all current methods of treatment for cancer.
https://doi.org/10.37469/0507-3758-2020-66-4-420-424
PDF (Русский)

References

Lightenstein L., Bernstein D. Unusual benign and malignant chondroid tumors of bone. A survey of some mesenchymal cartilage tumors and malignant chondroblastic tumors, including a few multicentric ones, as well as many atypical benign chondroblastomas and chondromyxoid fibromas. Cancer. 1959;12:1142-57. DOI: 10.1002/1097-0142(195911/12)12:6<1142::aid-cncr2820120610>3.0.co;2-d

Frezza A.M., Cesari M., Baumhoer D. et al. Mesenchymal chondrosarcoma: prognostic factors and outcome in 113 patients. A European Musculoskeletal oncology society study, eur. J Cancer. 2015;51(3):374-81. DOI: 10.1016/j.ejca.2014.11.007

Huvos A.G., Rosen G., Dabska M., Marcove R.C. Mesenchymal chondrosarcoma. A clinicopathologic analysis of 35 patients with emphasis on treatment. Cancer, 51 (7) (1983), pp. 1230-1237.

Nakashima Y, Unni K.K., Shives T.C. et al. Mesenchymal chondrosarcoma of bone and soft tissue. A review of 111 cases. Cancer, 57 (12) (1986), pp. 2444-2453.

Dantonello T.M., Int-Veen C., Leuschner I. et al. Mesenchymal chondrosarcoma of soft tissues and bone in children, adolescents, and young adults: experiences of the CWS and COSS study groups. Cancer, 112 (11) (2008), pp. 2424-2431.

Cesari M., Bertoni F., Bacchini P. et al. Mesenchymal chondrosarcoma. An analysis of patients treated at a single institution. Tumori, 93 (5) (2007), pp. 423-427.

Povysil C, Matejovsky Z, Trnka V. Mesenchymal chondrosarcoma. Cesk. Patol. 1986; 22(4):231-40. Czech.

Tsuda Y, Ogura K., Hakozaki M. et al. Mesenchymal chondrosarcoma: A Japanese Musculoskeletal oncology Group (JMOG) study on 57 patients. J. Surg. Oncol. 2017;115(6):760-767. DOI: 10.1002/jso.24567

Kawaguchi S., Weiss I., Lin P.P. et al. Radiation therapy is associated with fewer recurrences in mesenchymal chondrosarcoma. Clin Orthop Relat Res. 2014;472(3):856-64. DOI: 10.1007/s11999-013-3064-x

Thompson L.D. Small round blue cell tumors of the sinonasal tract: a differential diagnosis approach. Mod Pathol. 2017;30(s1):S1-S26. DOI: 10.1038/modpathol.2016.119

Горбань H.A., Попучиев В.В., Барышев В.В. Прогностические критерии течения плоскоклеточного рака гортани (обзор литературы). Опухоли головы и шеи. 2013. №1 С. 33-38.

Барышев В.В., Андреев В.Г., Севрюков Ф.Е. и др. Гломангиоперицитома полости носа. Клинический Случай. Голова и шея. 2018. №2 С. 42-44.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

© АННМО «Вопросы онкологии», Copyright (c) 2020