Predictive biomarkers of immune-related adverse events
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Keywords

review
immunotherapy
check-point inhibitors
immune-related adverse events
predictive biomarkers
HLA-genotypes
IL-10
gut microbiota

How to Cite

Zhukova, N., Orlova, R., Malkova, A., Kaledina, E., & Beliak, N. (2022). Predictive biomarkers of immune-related adverse events . Voprosy Onkologii, 68(1), 29–33. https://doi.org/10.37469/0507-3758-2022-68-1-29-33

Abstract

Taking into account widespread use of check-point inhibitors in real clinical practice, pharmacoeconomic issues, the incidence and grade of immune-related adverse events, there is an urgent need for using prognostic and predictive biomarkers of toxicity of immunotherapy. This review  presents  a  literature  review  of  the  databases such as PubMed, MEDLINE, Google Scholar, Springer. Articles were searched using the keywords: “predictive biomarkers of toxicity”, “immunotherapy”, “predictive markers of immune-related adverse events”. Subsequently the information obtained was analyzed in order to define possible predictive biomarkers of immune-related toxicity that could be used in real clinical practice.   

 

https://doi.org/10.37469/0507-3758-2022-68-1-29-33
##article.numberofdownloads## 19
##article.numberofviews## 211
pdf (Русский)

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