Transanal total mesorectal excision oncological results
pdf (Русский)

Keywords

rectal cancer;
oncological results,
total mesorectal excision,
transanal total mesorectal excision,
long-term results

How to Cite

Kazieva, L., Chernyshov , S., Alimova , Y., & Rybakov , E. (2022). Transanal total mesorectal excision oncological results. Voprosy Onkologii, 68(2), 200–208. https://doi.org/10.37469/0507-3758-2022-68-2-200-208

Abstract

Relevance. Transanal total mesorectal is a new surgical technique of rectal cancer treatment.

Purpose of research. To evaluate transanal total mesorectal excision oncological results.

Materials and methods. 66 patients with rectal cancer I–IV stage were included.

Results. Median follow-up was 42.9±22.8 (1–83.7) months. Progression of the disease was in 13 (19.7%) cases. Local recurrence rate was 5 (7.6%) with mean time to recurrence 14.2±11.3 (5–32.3) months. Distant metastasis was diagnosed in 10 (15.2%) cases, mean time when they were diagnosed was 15.04±12.09 (3.5–37.5) months. Combination of local recurrences and distant metastasis was in 2 (3%) cases. Seven (10.6%) patients died. Mean life expectancy was 27.3±17.2 (8.0–50.2) months. Five (7.5%) patients died because of progression of oncological disease. Mean life expectancy was 34.11±15.5 (15.5–50.2) months. Six-year local recurrence free, disease free and overall survival was 77, 87 и 84%, respectively. No risk factors of local recurrence were found.

Conclusion. Transanal total mesorectal excision oncological results are сomparable with conventional surgery, though further trials are necessary.

https://doi.org/10.37469/0507-3758-2022-68-2-200-208
pdf (Русский)

References

Sylla P, Rattner DW, Delgado S et al. NOTES transanal rectal cancer resection using transanal endoscopic microsurgery and laparoscopic assistance // SurgEndosc. 2010;24:1205–1210.

Tuech JJ, Karoui M, Lelong B et al. A step toward NOTES total mesorectal excision for rectal cancer: endoscopic transanal proctectomy //Ann surg. 2015;261:228–233.

Deijen CL, Tsai A, Koedam TW et al. Clinical outcomes and case volume effect of transanal total mesorectal excision for rectal cancer: a systematic review // Tech Coloproctol. 2016;20:811–824.

Helbach MV, Deijen CL, Velthuis S et al. Transanal total mesorectal excision for rectal carcinoma: short-term outcomes and experience after 80 cases // Surg Endosc. 2016;30(2):464–470.

Lacy АM, Tasende MM, Delgado S et al. Transanal total mesorectal excision for rectal cancer: outcomes after 140 patients // J Am Coll Surg. 2016;222(5):968–970.

Marks JH, Myers EA, Zeger EL et al. Long-term outcomes by a transanal approach to total mesorectal excision for rectal cancer // Surg Endosc. 2017;31:5248–5257.

Hol JC, Oostendorp SE, Tuynman J et al. Long-term oncological results after transanal total mesorectal excision for rectal carcinoma // Techniques in Coloproctology. 2019;23:903–911.

Larsen SG, Pfeffer F, Kørner H et al. Norwegian moratorium on transanal total mesorectal excision // Br J Surg. 2019;106(9):1120–1121.

Haynes SR, Lawler PG. An assessment of the consistency of ASA physical status classification allocation // Anaesthesia. 1995;50(3):195–199.

Amin MB, Edge SB, Greene FL et al. AJCC cancer staging manual, 8th ed. New York: Springer, 2017.

Quirke P, Steele R, Monson J et al. Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a 125 prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial // Lancet. 2009;373(9666):821–828.

Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey // Ann Surg. 2004;240(2):205–213.

Mandard AM, Dalibard F, Mandard JC et al. Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations // Cancer. 1994;73(11):2680–2686.

Heald RJ. A new solution to some old problems: transanal TME // Tech Coloproctol. 2013;17:257–258.

Wexner SD, Berho M. Transanal TAMIS total mesorectal excision (TME) — a work in progress // Tech Coloproctol. 2014;18:423–425.

Roodbeen SX, Penna M, Dieren S. Local Recurrence and Disease-Free Survival After Transanal Total Mesorectal Excision: Results From the International TaTME Registry // J Natl Compr Canc Netw. 2021;17;jnccn20505. doi:10.6004/jnccn.2021.7012

Oostendorp SE, Belgers HJ, Bootsma BT et al. Locoregional recurrences after transanal total mesorectal excision of rectal cancer during implementation // Br J Surg. 2020;107:1211–1220.

Казиева Л.Ю., Чернышов С.В., Рыбаков Е.Г. и др. Кривая обучения трансанальной тотальной мезоректумэктомии // Колопроктология. 2020;2:62–68 [Kazieva LYu, Chernyshov SV, Rybakov EG et al. Transanal total mesorectal excision learning curve // Coloproctology. 2020;2:62–68 (In Russ.)].

Adamina M, Buchs NC, Penna M et al. St.Gallen consensus on safe implementation of transanal total mesorectal excision // Surgical Endoscopy. 2018;32:1091–1103.

Tsai AY, Mavroveli S, Miskovic D et al. Surgical quality assurance in COLOR III: standardization and competency assessment in a randomized controlled trial // Ann Surg. 2019;270:768–774.

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