Vol. 69 No. 1 (2023), REVIEWS

Vol. 69 No. 1 (2023)

Prospects for the application of microRNAs (miR-371, miR-302, miR-372, miR-367) as biomarkers in patients with germ cell tumors

REVIEWS

https://doi.org/10.37469/0507-3758-2023-69-1-24-29

Published 07.03.2023

Valentina Andreevna Zagoruiko ⁺⁻
Alexander Konstantinovich Nosov
Margarita Sergeevna Knyazeva
Nikita Andreevich Shchekuteev
Artur Yurevich Malygin
Dmitry Alekseevich Savkin
Svetlana Anatolevna Protsenko

Valentina Andreevna Zagoruiko

ФГБУ "НМИЦ онкологии им.Н.Н.Петрова"

https://orcid.org/0000-0001-7508-8383

Alexander Konstantinovich Nosov

Margarita Sergeevna Knyazeva

Nikita Andreevich Shchekuteev

Artur Yurevich Malygin

Dmitry Alekseevich Savkin

Svetlana Anatolevna Protsenko

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##article.numberofviews## 123

pdf (Русский)

Keywords

microRNA
tumor markers
biomarker
germ cell tumors

How to Cite

Zagoruiko , V. A., Nosov, A. K., Knyazeva , M. S., Shchekuteev , N. A., Malygin , A. Y., Savkin , D. A., & Protsenko , S. A. (2023). Prospects for the application of microRNAs (miR-371, miR-302, miR-372, miR-367) as biomarkers in patients with germ cell tumors. Voprosy Onkologii, 69(1), 24–29. https://doi.org/10.37469/0507-3758-2023-69-1-24-29

Abstract

This review presents the latest clinical studies data exploring microRNA that can have a potential value as biological marker in patients with germ cell tumors.

Common tumor markers in the diagnosis and treatment of patients with germ cell tumors are not sensitive and not specific enough. This induced studies and search for new tumor markers. One of such biomarkers is microRNA. These are single-stranded RNAs that inhibit protein synthesis or initiate mRNA degradation.

Current clinical studies suggest that these molecules can be used in clinical practice and can potentially influence clinical decision-making in the treatment of patients with germ cell tumors.

https://doi.org/10.37469/0507-3758-2023-69-1-24-29

##article.numberofdownloads## 126

##article.numberofviews## 123

pdf (Русский)

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