Abstract
Introduction. Cell morphology has been a crucial area of study since the invention of the microscope, evolving significantly with the advancement of ultramicroscopic techniques. This study analyzes the top 100 most cited publications on cell morphology to uncover key research trends and influential works from the past three decades.
Materials and Methods. A bibliometric analysis was conducted using the Web of Science Core Collection database, covering articles published from January 1985 to April 2023. From an initial pool of 1,251,024 articles, the top 100 most cited publications were identified. Data on publication year, citation counts, journals, authors, geographical distribution, institutions, and keywords were extracted. VOSviewer and Bibliometrix were used for statistical analysis.
Results. The top 100 articles were published in 43 journals, including high-impact publications such as Nature, Science, and Cell. The most cited article, "Matrix Elasticity Directs Stem Cell Lineage Specification," had 9,832 citations. The United States contributed 70 articles. Key research themes identified included the mechanical microenvironment, stem cell research, and advanced imaging techniques.
Conclusion. This study highlights the importance of the extracellular matrix and signaling pathways in determining cell morphology. It underscores the predominant role of high-impact journals and emphasizes the need for multidisciplinary approaches in future research on cell morphology.
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