NEOADJUVANT SYSTEMIC THERAPY FOR BREAST CANCER (RETROSPECTIVE AND PROSPECTIVE ANALYSIS)
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Keywords

BREAST CANCER
NEOADJUVANT ENDOCRINE THERAPY
CHEMOTHERAPY

How to Cite

Semiglazov, V., Gigolaeva, L., Tabagua, T., Zernov, K., Komyakhov, A., Nikolaev, K., Bessonov, A., Ivanov, V., Ivanova, O., Zhiltsova, Y., Dashyan, G., Krivorotko, P., & Semiglazov, V. (2017). NEOADJUVANT SYSTEMIC THERAPY FOR BREAST CANCER (RETROSPECTIVE AND PROSPECTIVE ANALYSIS). Voprosy Onkologii, 63(2), 256–260. https://doi.org/10.37469/0507-3758-2017-63-2-256-260

Abstract

There are presented the immediate and long-term results of neoadjuvant endocrine therapy versus chemotherapy in ER+ breast cancer and chemotherapy (carboplatin + taxane) at triple-negative tumor subtype. We marked a tendency of improving a 10-year disease-free survival at luminal A subtype in patients who received endocrine therapy compared with chemotherapy (72.8% vs. 53.9%; p=0.062). Only 5.9% of patients with ER+ /HER2+ co-expression, who received target therapy, reached complete regression (pCR). There was a greater frequency of pCR, among patients with triple-negative breast cancer who received neoadjuvant chemotherapy with paclitaxel + carboplatin.
https://doi.org/10.37469/0507-3758-2017-63-2-256-260
PDF (Русский)

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