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The efficacy of SPECT-CT with 99mTc-MIBI for detecting axillary lymph node (LN) involvement was evaluated in 184 patients with primary breast cancer. All patients were operated with histological examination of axillary LNs. During statistical analysis we determined correlation between LN metastases and various diagnostic and clinical characteristics. SPECT-CT signs of LN involvement were as follows: short axis more than 10 mm, cortical thickness more than 4mm, solid structure, round shape, intensive tracer uptake. More than 2 metastatic LNs were considered as plural metastatic damage. The complex model for evaluation axillary LN involvement was elaborated. The use this data in our study showed that SPECT-CT 99mTc-MIBI could correctly exclude 2 or more metastatic LNs in 96% breast cancer patients.References
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