Abstract
Breast cancer ranks the first place in the structure of morbidity and mortality from malignant tumors of the female population of the Republic of Uzbekistan. According to data of 598 patients with breast cancer biological features of HER2/ neu-positive breast cancer were studied in 109 (18.2 %) cases/ In addition in 31 cases the immunohistochemical analysis on HER2/neu was established as “+2”, the FISH-test was not conducted. Among patients with HER2/neu-overexpressing breast cancer the patients of the indigenous ethnos (Uzbeks) were 54 %. In general among patients with HER2/neu-positive breast cancer the prevalence of locally advanced forms of the disease was noted. Luminal B with HER2/neu-overexpression (45 %) - the average age of patients was 50.4 ± 13.2 years, the average level of Ki67 was 37.8 % ; HER2/neu-overexpress-ing breast cancer (55 %) - the average age of patients was 51.3 ± 9.2 years, the average level of Ki67 was 47.1 %.References
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