PRECLINICAL AND CLINICAL STUDY OF EXTRACELLULAR DNA IN CANCER AND OTHER DISEASES ASSOCIATED WITH APOPTOSIS DISORDER
Vol. 64 No. 3 (2018), ORIGINAL ARTICLES. B. EXPERIMENTAL RESEARCH
Vol. 64 No. 3 (2018)

PRECLINICAL AND CLINICAL STUDY OF EXTRACELLULAR DNA IN CANCER AND OTHER DISEASES ASSOCIATED WITH APOPTOSIS DISORDER

ORIGINAL ARTICLES. B. EXPERIMENTAL RESEARCH
https://doi.org/10.37469/0507-3758-2018-64-3-435-439
Published 01.03.2018
Irina Vasileva
N.N. Petrov National Medical Research Center of Oncology
Viktor Bespalov
N.N. Petrov National Medical Research Center of Oncology, ITMO University
PDF (Русский)

Keywords

EXTRACELLULAR DNA
APOPTOSIS
PRECANCEROUS DISEASES
PATHOLOGY
NUCLEOSOMES

How to Cite

Vasileva, I., & Bespalov, V. (2018). PRECLINICAL AND CLINICAL STUDY OF EXTRACELLULAR DNA IN CANCER AND OTHER DISEASES ASSOCIATED WITH APOPTOSIS DISORDER. Voprosy Onkologii, 64(3), 435–439. https://doi.org/10.37469/0507-3758-2018-64-3-435-439
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Abstract

Oncological diseases at all stages of carcinogenesis are accompanied by violation of apoptosis processes. Drug and radiotherapy activates the apoptosis of tumor cells. This study presents the results of extracellular DNA changes after exposure to ionizing radiation and low-frequency noise are presented, administration of vitamins; in animals with benign prostatic hyperplasia, with ovarian cancer; in clinical studies in patients with chronic obstructive pulmonary disease, and in acute disorders of cerebral circulation. The possibilities of determination of extracellular DNA for the evaluation of the action of carcinogens, the complex diagnosis of precancerous diseases, the progression of precancerous diseases and malignant tumors are considered.
https://doi.org/10.37469/0507-3758-2018-64-3-435-439
PDF (Русский)

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