PRECLINICAL AND CLINICAL STUDY OF EXTRACELLULAR DNA IN CANCER AND OTHER DISEASES ASSOCIATED WITH APOPTOSIS DISORDER

ORIGINAL ARTICLES. B. EXPERIMENTAL RESEARCH

https://doi.org/10.37469/0507-3758-2018-64-3-435-439

Published 01.03.2018

Irina Vasileva⁺⁻
Viktor Bespalov⁺⁻

Irina Vasileva

N.N. Petrov National Medical Research Center of Oncology

Viktor Bespalov

N.N. Petrov National Medical Research Center of Oncology, ITMO University

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Keywords

EXTRACELLULAR DNA
APOPTOSIS
PRECANCEROUS DISEASES
PATHOLOGY
NUCLEOSOMES

How to Cite

Vasileva, I., & Bespalov, V. (2018). PRECLINICAL AND CLINICAL STUDY OF EXTRACELLULAR DNA IN CANCER AND OTHER DISEASES ASSOCIATED WITH APOPTOSIS DISORDER. Voprosy Onkologii, 64(3), 435–439. https://doi.org/10.37469/0507-3758-2018-64-3-435-439

Abstract

Oncological diseases at all stages of carcinogenesis are accompanied by violation of apoptosis processes. Drug and radiotherapy activates the apoptosis of tumor cells. This study presents the results of extracellular DNA changes after exposure to ionizing radiation and low-frequency noise are presented, administration of vitamins; in animals with benign prostatic hyperplasia, with ovarian cancer; in clinical studies in patients with chronic obstructive pulmonary disease, and in acute disorders of cerebral circulation. The possibilities of determination of extracellular DNA for the evaluation of the action of carcinogens, the complex diagnosis of precancerous diseases, the progression of precancerous diseases and malignant tumors are considered.

https://doi.org/10.37469/0507-3758-2018-64-3-435-439

##article.numberofdownloads## 34

##article.numberofviews## 72

PDF (Русский)

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