OPPORTUNITIES IN DIAGNOSTICS OF PANCREATIC METASTATIC TUMORS BY CYTOLOGICAL METHOD
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Keywords

PANCREAS
METASTATIC LESIONS
FINE NEEDLE ASPIRATIONS
OYTOLOGICAL DIAGNOSTIC
CYTOLOGICAL EXAMINATION

How to Cite

Mikhetko, A., Ivko, O., Petrik, S., Tkachenko, O., Grinkevich, M., Sidorova, A., Petrik, Y., Shalina, Y., & Mikhetko, A. (2019). OPPORTUNITIES IN DIAGNOSTICS OF PANCREATIC METASTATIC TUMORS BY CYTOLOGICAL METHOD. Voprosy Onkologii, 65(3), 409–413. https://doi.org/10.37469/0507-3758-2019-65-3-409-413

Abstract

Our study includes results of 152 pancreatic fine needle aspirations of solid and cystic tumors, from 149 patients of the N.N. Petrov Cancer Research Center for the 3-year period (2016 - 2018). Representative cell material for morphological studies was obtained in 97.4% of cases. The results of cytological examination of 111 patients with pancreatic tumors were compared with histological data. The effectiveness of cytological examination was 96.1%, sensitivity - 95.6%, specificity -100%. Metastatic lesions were presented in 9% (9 patients). In 9 diagnostically proven cases, the cytological result was correct 8 times. Cytological examination with immunocytochemistry is a valid and accurate diagnostic procedure for the evaluation of pancreatic tumors including metastatic lesions.
https://doi.org/10.37469/0507-3758-2019-65-3-409-413
##article.numberofdownloads## 40
##article.numberofviews## 154
PDF (Русский)

References

Двойникова Е.Р., Агапов М.Ю., Стегний К.В. Оценка эффективности эндосонографии и тонкоигольной пункции под контролем эндоскопической ультрасонографии при солидных образованиях поджелудочной железы на этапе освоения методики // Тихоокеанский медицинский журнал. - 2016. - № 1. - С. 66-68.

Попов С.А., Павловский А.В., Урбанский А.И. Эффективность чрескожной трепанобиопсии в диагностике новообразований поджелудочной железы // Вестник хирургии им. И.И. Грекова. - 2014. - №1. - С. 84-88.

Шапиро Н.А., Батороев Ю.К., Дворниченко В.В. Цитологическая диагностика опухолей печени, желчного пузыря и поджелудочной железы: цветной атлас. Под. ред. Н.А.Шапиро. - М., 2012. - 260 с.

Alzahrani M.A., Schmulewitz N., Grewal S. et al. Metastases to the pancreas: the experience of a high volume center and a review of the literature // J. Surg. Oncol. - 2012. - Vol. 105. - № 2. - P. 156-161.

Ardengh J.C., Lopes C.V., Kemp R. et al. Accuracy of endoscopic ultrasound-guided fine-needle aspiration in the suspicion of pancreatic metastases // BMC Gastroenterology. - 2013. - Vol. 13. - P. 63.

Atiq M., Bhutani M.S., Ross W.A. Role of Endoscopic Ultrasonography in Evaluation of Metastatic Lesions to the Pancreas: A Tertiary Cancer Center Experience // Pancreas. - 2013. - Vol. 42. - № 2. - P 516-523.

Chan E.S., Alexander J., Swanson P.E. et al. PDX-1, CDX- 2, TTF-1, and CK7: a reliable immunohistochemical panel for pancreatic neuroendocrine neoplasms // Am. J. Surg. Pathol. - 2012. - Vol. 36. - № 5. - P. 737-743.

Ganjei-Azar P., Nadji M. Color Atlas of Immunocytochemistry in Diagnostic Cytology // Springer, 2007. - P. 296.

Gavini H., Arukala V.D., Stewart J., Lee J.H. Medulloblastoma metastatic to the pancreas: a case report // Gastrointestinal Intervention. - 2014. - Vol. 3. - №1. - P. 116-119.

Hou Y, Shen R., Tonkovich D., Li Z. Endoscopic ultrasound-guided fine-needle aspiration diagnosis of secondary tumors involving pancreas: an institution's experience // Journal of the American Society of Cytopathology. - 2018. - Vol. 7. - № 5. - P. 261-267.

Layfield L.J., Jarboe E.A. Cytopathology of the pancreas: neoplastic and nonneoplastic entities // Annals of Diagnostic Pathology. - 2010. - Vol. 14. - № 2. - P. 140-151.

Layfield L.J., Hirschowitz S.L., Adler D.G. Metastatic disease to the pancreas documented by endoscopic ultrasound guided fine-needle aspiration: a seven-year experience // Diagn. Cytopathol. - 2012. - Vol. 40. - № 3. - P. 228-233.

Lin F, Staerkel G. Cytologic Criteria for welldifferentiated adenocarcinoma of the pancreas in fine-needle aspiration biopsy specimens // Cancer (Cancer Cytopathology). -2003. - Vol. 99. - № 1. - P. 44 -50.

Mizuno N., Hara K., Hijioka S. et al. Current Concept of Endoscopic Ultrasound-Guided Fine Needle Aspiration for Pancreatic Cancer // Pancreatology. - 2011. - Vol. 11. -№ 2. - P. 40-46.

Olson M.T., Wakely Jr P.E., Ali S.Z. Metastases to the pancreas diagnosed by fine-needle aspiration // Acta. Cytol. - 2013. - Vol. 57. - P. 473 - 480.

Pang JC, Roh MH. Metastases to the pancreas encountered on endoscopic ultrasound-guided, fine-needle aspiration // Arch. Pathol. Lab. Med. - 2015. -Vol. 139. - № 10. - P. 1248 - 1252.

Smith A.L., Odronic S.I., Springer B.S., Reynolds J.P. Solid tumor metastases to the pancreas diagnosed by FNA: a single-institution experience and review of the literature // Cancer Cytopathol. - 2015. - Vol. 123. -№ 6. - P. 347-355.

Syed Z. Ali, Yener S. Erozan, Ralph H. Hruban. Atlas of pancreatic cytopathology with histopathologic correlations / Ali, Syed Z. - New York: Demos Medical Publishing, 2009. -277 с.

Waters L., Si Q., Caraway N. et al. Secondary tumors of the pancreas diagnosed by endoscopic ultrasound-guided fine-needle aspiration: a 10-year experience // Diagn Cytopathol. - 2014. - Vol. 42. - № 9. - P. 738-743.

Yang R.Y, Ng D., Jaskolka J.D. et al. Evaluation of percutaneous ultrasound-guided biopsies of solid mass lesions of the pancreas: a center's 10-year experience // Clinical Imaging. - 2015. - Vol. 39. - P. 62-65.

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