Clinical Case: Perioperative Fluorescein ICG-Angiography of the Ureters in a Patient with an Orthotopic Neobladder after Repeated Ureteroileoanastomotic Strictures
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Keywords

ureter
reconstruction
fluorescence
indocyanine green
bladder cancer

How to Cite

Rumiantseva, D. I., Mamizhev, E. M., Bashmakova, I. P., & Nosov, A. K. (2025). Clinical Case: Perioperative Fluorescein ICG-Angiography of the Ureters in a Patient with an Orthotopic Neobladder after Repeated Ureteroileoanastomotic Strictures. Voprosy Onkologii, 71(1), 199–204. https://doi.org/10.37469/0507-3758-2025-71-1-199-204

Abstract

Introduction. Radical cystectomy is one of the most complex operations in surgical oncology and urology. The complication rate of the orthotopic urinary reservoir is 40-50 %, including ureteroileoanastomotic strictures in up to 20 % of cases. Perioperative tissue fluorescence allows reliable assessment of the degree of tissue perfusion. We have developed and patented a method for perioperative visualization of the ureter using ICG angiography.

Case description. A 60-year-old man presented with problems with spontaneous urination 7 years after complex treatment for muscle-invasive bladder cancer, including transurethral resection, neoadjuvant chemotherapy and radical cystectomy with formation of an orthotopic urinary reservoir using the Studer technique. Examination revealed repeated strictures of both ureteroileoanastomoses and the presence of nephrostomy drainages. Surgical intervention was performed in the form of laparoscopic reimplantation of both ureters into the orthotopic reservoir using the technique of perioperative fluorescent ICG diagnosis of the ureters. There were no immediate complications during the surgical and post-operative period. Currently, the patient is under dynamic follow-up for more than three years with no evidence of recurrence of ureteroileoanastomotic strictures.

Conclusion. Perioperative ICG angiography is an effective and affordable method for the diagnosis and prevention of postoperative complications associated with ureteroileoanastomosis.

https://doi.org/10.37469/0507-3758-2025-71-1-199-204
##article.numberofdownloads## 17
##article.numberofviews## 59
pdf (Русский)

References

Cerruto M.A., D'Elia C., Siracusano S., et al. Is Health-related quality of life after radical cystectomy using validated questionnaires really better in patients with ileal orthotopic neobladder compared to ileal conduit: a meta-analysis of retrospective comparative studies. Curr Urol. 2017; 10(2): 57-68.-DOI: https://doi.org/10.1159/000447153.

Porena M., Mearini L., Zucchi A., et al. Perugia ileal neobladder: functional results and complications. World J Urol. 2012; 30(6): 747-752.-DOI: https://doi.org/10.1007/s00345-012-0985-z.

Kim S.H., Yu A., Jung J.H., et al. Incidence and risk factors of 30-day early and 90-day late morbidity and mortality of radical cystectomy during a 13-year follow-up: a comparative propensity-score matched analysis of complications between neobladder and ileal conduit. Jpn J Clin Oncol. 2014; 44(7): 677-685.-DOI: https://doi.org/10.1093/jjco/hyu051.

Moeen A.M., Safwat A.S., Gadelmoula M.M., et al. Does the site of the orthotopic neobladder outlet matter? A prospective randomized comparative study. Eur J Surg Oncol. 2018; 44(6): 847-852.-DOI: https://doi.org/10.1016/j.ejso.2018.01.094.

Zhong H., Shen Y., Yao Z., et al. Long-term outcome of spiral ileal neobladder with orthotopic ureteral reimplantation. Int Urol Nephrol. 2020; 52(1): 41-49.-DOI: https://doi.org/10.1007/s11255-019-02296-x.

Мудунов А.М., Гельфанд И.М., Кропотов М.А., et al. Улучшение диагностики «скрытого» метастазирования при плоскоклеточном раке слизистой оболочки полости рта сТ1-2N0М0. Опухоли головы и шеи. 2022; 12(1): 12-25.-DOI: https://doi.org/10.17650/2222-1468-2022-12-1-12-25. [Mudunov A.M., Gelfand I.M., Kropotov M.A., et al. Improved diagnostics of «concealed» metastases in patients with сТ1–2N0М0 oral squamous cell carcinoma. Head and Neck Tumors (HNT). 2022; 12(1): 12-25.-DOI: https://doi.org/10.17650/2222-1468-2022-12-1-12-25. (In Rus)].

Алексеев М.В., Рыбаков Е.Г., Севостьянов С.И. Интраоперационная флуоресцентная ангиография с индоцианином зеленым – метод профилактики несостоятельности колоректального анастомоза (систематический обзор литературы). Колопроктология. 2017; (4): 82-87.-DOI: https://doi.org/10.33878/2073-7556-2017-0-4-82-87. [Alekseev M.V., Rybakov E.G., Sevostiyanov S.I. Indocyanine green intraoperative angiography as prophilaxis of colorectal anastomotic leakage (a systematic review). Koloproktologia. 2017; (4): 82-87.-DOI: https://doi.org/10.33878/2073-7556-2017-0-4-82-87. (In Rus)].

Kitai T., Inomoto T., Miwa M., Shikayama T. Fluorescence navigation with indocyanine green for detecting sentinel lymph nodes in breast cancer. Breast Cancer. 2005; 12(3): 211-215.-DOI: https://doi.org/10.2325/jbcs.12.211.

Тихоновская М. Н., Шевчук А. С. Исследование сторожевых лимфатических узлов при раннем раке яичников: первый опыт ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России. Тазовая хирургия и Онкология. 2022; 12(3): 19-25.-DOI: https://doi.org/10.17650/2686-9594-2022-12-3-19-25. [Tikhonovskaya M.N., Shevchuk A.S. Sentinel lymph node detection in early stage ovarian cancer: the primary experience in N. N. Blokhin national medical Research Center of Oncology. Pelvic Surgery and Oncology. 2022; 12(3): 19-25.-DOI: https://doi.org/10.17650/2686-9594-2022-12-3-19-25. (In Rus)].

Polom W., Migaczewski M., Skokowski J., et al. Multispectral imaging using fluorescent properties of indocyanine green and methylene blue in colorectal surgery-initial experience. J Clin Med. 2022; 11(2): 368..-DOI: https://doi.org/10.3390/jcm11020368.

Jafari M.D., Wexner S.D., Martz J.E., et al. Perfusion assessment in laparoscopic left-sided/anterior resection (PILLAR II): a multi-institutional study. J Am Coll Surg. 2015; 220(1): 82-92.e1.-DOI: https://doi.org/10.1016/j.jamcollsurg.2014.09.015.

Rausa E., Zappa M.A., Kelly M.E., et al. A standardized use of intraoperative anastomotic testing in colorectal surgery in the new millennium: is technology taking over? A systematic review and network meta-analysis. Tech Coloproctol. 2019; 23(7): 625-631.-DOI: https://doi.org/10.1007/s10151-019-02034-6.

Tobis S., Knopf J.K., Silvers C.R., et al. Near infrared fluorescence imaging after intravenous indocyanine green: initial clinical experience with open partial nephrectomy for renal cortical tumors. Urology. 2012; 79(4): 958-964.-DOI: https://doi.org/10.1016/j.urology.2011.10.016.

Shah S.H., Movassaghi K., Skinner D., et al. Ureteroenteric strictures after open radical cystectomy and urinary diversion: the University of Southern California experience. Urology. 2015; 86(1): 87-91.-DOI: https://doi.org/10.1016/j.urology.2015.03.014.

Anderson C.B., Morgan T.M., Kappa S., et al. Ureteroenteric anastomotic strictures after radical cystectomy-does operative approach matter? J Urol. 2013; 189(2): 541-547.-DOI: https://doi.org/10.1016/j.juro.2012.09.034.

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