Keywords
How to Cite
Abstract
We present the findings of a dynamic study of the key parameters of quality of life in 24 patients (average age 44.42±3.13 years; 14 (58.3%) males) with pelvic bone tumors who underwent limb salvage [organ preservation] treatment at the National Medical Research Centre of Oncology named after N.N. Blokhin to the extent of tumor removal and restoration of the defect with individual implants created by means of three-dimensional printing. Used were two internationally accepted diagnostic tools for assessing quality of life in cancer patients and the author's «Quality-of-Life Questionnaire for patients who underwent surgery on the pelvic bones» covering 28 indices. The findings of the study testify to there being no significant positive dynamics of the general quality of life measure, decrease in satisfaction with physical and social activity in patients, which may be related to unreasonably high patient expectations regarding success in life after limb salving surgery; there is clinically justified increase in neurological symptoms. Correlation analysis of life quality indices with other characteristics of patients was performed. It turned out that the severity of pain after endoproshetics is negatively associated with the general physical state of the patient and the functional result of endoproshetics, and positively — with age and compliance. A clinical example of quality of life dynamics after endoprosthetics with good functional result is presented.
References
Алиев М.Д., Сушенцов Е.А. Современная онкоортопедия // Саркомы костей, мягких тканей и опухоли кожи. 2012;4:3–10 [Aliev MD, Sushentsov EA. Modern onco-orthopedics // Sarcomas of bones, soft tissues and skin tumors. 2012;4:3–10 (In Russ.)].
Алиев М.Д., Мусаев Э.Р., Сушенцов Е.А. Хирургическое лечение метастазов рака почки в кости таза // Онкоурология. 2006;2:21–25 [Aliev MD, Musaev ER, Sushentsov EA. Surgical treatment of metastases of kidney cancer in the pelvic bone // Oncourology. 2006;2:21–25 (In Russ.)].
Сушенцов Е.А., Мусаев Э.Р., Софронов Д.И. и др. Замещение дефектов костей таза у онкологических больных индивидуальными имплантами. Опыт лечения 20 пациентов // Саркомы костей, мягких тканей и опухоли кожи. 2020;1:5–13 [Sushentsov EA, Musaev ER, Sofronov DI et al. Replacement of pelvic bone defects in cancer patients with individual implants. Experience in the treatment of 20 patients // Sarcomas of bones, soft tissues and tumors of the skin. 2020;1:5–13 (In Russ.)].
Усманова Е.Б., Сушенцов Е.А., Щелкова О.Ю. Качество жизни пациентов с опухолями костей // Саркомы костей, мягких тканей и опухоли кожи. 2015;1:55–61 [Usmanova EB, Sushentsov EA, Shchelkova OYu. Quality of life in patients with bone tumors // Sarcomas of bones, soft tissues and skin tumors. 2015;1:55–61(In Russ.)].
Усманова Е.Б., Щелкова О.Ю., Исурина Г.Л. и др. Опросник качества жизни для пациентов с онкоортопедической патологией // Консультативная психология и психотерапия. 2019;2(104):147–166 [Usmanova EB, Shchelkova OYu, Isurina GL. et al. Questionnaire for the quality of life for patients with onco-orthopedic pathology // Consultative psychology and psychotherapy. 2019;2(104):147–166 (In Russ.)].
Щелкова О.Ю., Усманова Е.Б. Качество жизни и психологические характеристики больных с опухолевым поражением костей // Вестник Санкт-Петербургского университета, Серия 12. 2015;3:64–76 [Shchelkova OYu, Usmanova EB. Quality of life and psychological characteristics of patients with bone tumors // Bulletin of St. Petersburg University, Series 12. 2015;3:64–76 (In Russ.)].
Aaronson NK, Ahmedzai S, Bergman B. The European Organisation for Research and Treatment of Cancer QLQ-C30: A quality of life instrument for use in international clinical trilas in oncology // Journal of National Cancer lnstitute. 1993;85:365–375.
Abudu A, Grimer RJ, Cannon SR et al. Reconstruction of the hemipelvis after the excision of malignant tumours // J Bone Joint Surg. 1997;79:773-779.
Bakas T, McLennon SM, Carpenter JS et al. Systematic review of health-related quality of life models // Health Qual Life Outcomes. 2012;10:134.
Fayers P, Aarson N, Bjordal K, Sullivan M. QLQ C-30 Scoring Manual / EORTC Study Group on Quality of Life. Brussels, 1995:50.
Haidukewych GJ. Metastatic disease around the hip: maintaining quality of life // J Bone Joint Surg Br. 2012;22–25.
Hawker GA, Mian S, Kendzerska T, French M. Measures of adult pain: Visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), Short-Form McGill Pain Questionnaire (SF-MPQ), Chronic Pain Grade Scale (CPGS), Short Form-36 Bodily Pain Scale (SF-36 BPS), and Measure of Intermittent and Constant Osteoarthritis Pain (ICOAP) // Arthritis Care Res (Hoboken). 2011;63:240–252.
Karnofsky DA, Burchenal JH. The clinical evaluation of chemotherapeutic agents in cancer. MacLeod CM (Ed), Evaluation of Chemotherapeutic Agents. Columbia University Press, 1949;196.
Kim D, Lim JY, Shim KW et al. Sacral Reconstruction with a 3D-Printed Implant after Hemisacrectomy in a Patient with Sacral Osteosarcoma: 1-Year Follow-Up Result // Yonsei Med J. 2017;58(2):453–457.
Liu X, Liu Y et al. Combined Application of Modified Three-Dimensional Printed Anatomic Templates and Customized Cutting Blocks in Pelvic Reconstruction After Pelvic Tumor Resection // J Arthroplasty. 2019;34(2):338–345.
McKenzie L, van der Pol M. Mapping the EORTC QLQ C-30 onto the EQ-5D instrument: the potential to estimate QALYs without generic preference data // Value Health. 2009;12(1):167–171.
Müller DA, Capanna R. The surgical treatment of pelvic bone metastases // Adv Orthop. 2015(1);10.
Prabowo Y, Asril E, Wikanjaya R. Functional outcome of operative treatment for pelvic metastatic bone disease from primary thyroid cancer: A case series // Int J Surg Case Rep. 2020;66:288–297.
Price CH, Jaffe GM. Incidence of bone sarcoma in SW England, 1946–74, in relation to age, sex, tumor site and histology // Br J Cancer. 1977;36:511–22.
Sabourin M, Biau D, Babinet A. Surgical management of pelvic primary bone tumors involving the sacroiliac joint // Orthop Traumatol Surg Res. 2009;95(4):284–92.
Salunke AA, Shah J, Warikoo V. Surgical management of pelvic bone sarcoma with internal hemipelvectomy: Oncologic and Functional outcomes // J Clin Orthop Trauma. 2017;8(3):249–253.
Scott J, Huskisson EC. Graphic representation of pain // Pain. 1976;2(2):175–184.
Watkins RG, Brien JPO, Jones D. Comparisons of preoperative and postoperative MMPI data in chronic back pain patient // Spine. 1986;11(4):385–390.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
© АННМО «Вопросы онкологии», Copyright (c) 2022