Novikov, R., Ponomareva, O., Novikov, S., Vasilii, Protoschak, V., Арсеньев, А. И., Ilyin, N., Samartseva, E., Merezhko, Y., Sergey, & Nikolay. (2023). MRI Findings of the Results of Transperineal Insertion of a «Spacer» Based on Synthetic Collagen of Animal Origin to Optimize Radiation Treatment of Prostate Cancer. Voprosy Onkologii, 69(6), 1039–1048. https://doi.org/10.37469/0507-3758-2023-69-6-1039-1048

Abstract

Aim. To evaluate the results of collagen spacer implantation, using magnetic resonance image (MRI) analysis.

Materials and methods. The study included 50 patients with localized prostate cancer who had a spacer placed between the rectum and prostate before stereotactic radiotherapy (SRT) was performed. Introduction of the spacer based on synthetic collagen of animal origin was conducted according to the standard procedure under US control. In all cases, topometric MRI was done after spacer placement.

Results. We conducted standard procedure to assess the quality of the spacer insertion using MRI imaging that represent various cases of excellent, acceptable and unsatisfactory spacer placement. Complications occurred in 2 out of 50 cases, specifically related to inserting an animal collagen-based spacer into the rectum wall. These complications did not manifest clinically and did not affect the treatment strategy.

Conclusion. Presented MRI images illustrate efficacy and safety of collagen spacers in routine clinical practice.

https://doi.org/10.37469/0507-3758-2023-69-6-1039-1048

pdf (Русский)

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