CYTOLOGICAL AND IMMUNOCYTOCHEMICAL DIAGNOSIS OF TUMOR PLEURITIS

ORIGINAL ARTICLES. A. PROTOCOLS OF CLINICAL RESEARCH

https://doi.org/10.37469/0507-3758-2017-63-6-894-899

Published 01.06.2017

Viktor Novik⁺⁻
A. Nefedova⁺⁻
Ye. Yakubo⁺⁻
O. Ivanov⁺⁻
Yekaterina Shalina⁺⁻
Anna Vladimirova⁺⁻
Alla Mikhetko⁺⁻
Larisa Krasilnikova⁺⁻
Viktor Klimenko⁺⁻
T. Lindeberg⁺⁻

Viktor Novik

N.N. Petrov National Medical Research Center of Oncology

A. Nefedova

N.N. Petrov National Medical Research Center of Oncology

Ye. Yakubo

N.N. Petrov National Medical Research Center of Oncology

O. Ivanov

N.N. Petrov National Medical Research Center of Oncology

Yekaterina Shalina

N.N. Petrov National Medical Research Center of Oncology

Anna Vladimirova

N.N. Petrov National Medical Research Center of Oncology

Alla Mikhetko

N.N. Petrov National Medical Research Center of Oncology

Larisa Krasilnikova

N.N. Petrov National Medical Research Center of Oncology

Viktor Klimenko

N.N. Petrov National Medical Research Center of Oncology

T. Lindeberg

N.N. Petrov National Medical Research Center of Oncology

##article.numberofdownloads## 51

##article.numberofviews## 131

PDF (Русский)

Keywords

TUMOR PLEURITIS
CYTOLOGICAL DIAGNOSIS
IMMUNOCYTOCHEMICAL STUDY

How to Cite

Novik, V., Nefedova, A., Yakubo, Y., Ivanov, O., Shalina, Y., Vladimirova, A., Mikhetko, A., Krasilnikova, L., Klimenko, V., & Lindeberg, T. (2017). CYTOLOGICAL AND IMMUNOCYTOCHEMICAL DIAGNOSIS OF TUMOR PLEURITIS. Voprosy Onkologii, 63(6), 894–899. https://doi.org/10.37469/0507-3758-2017-63-6-894-899

Abstract

Cytological examination of smears from the sediment after centrifugation of pleural fluids was performed in 479 patients who underwent examination and treatment at our institution in 2014-2016. In 249 (52%) patients tumor cells were not detected in smears, in 230 (48%) observations a suspicion (28 observations) or a confident conclusion (202 observations) on the presence of malignant tumor cells in the exudates was cytologically expressed. In 38 cases immunocytochemical studies was additionally performed. In two observations a false-negative conclusion about the absence of tumor cells in smears was expressed. The sensitivity of the cytological study in the diagnosis of malignant pleuritis was 99.0%. Affirmative cytological conclusions on the presence of malignant pleuritis were given in 87.0% of observations, suspicious cytological responses - in 12.0% of cases. Immunocytochemical studies significantly expanded the possibilities of cytological research and were of great importance in the diagnosis of metastases of tumors of unknown primary localization.

https://doi.org/10.37469/0507-3758-2017-63-6-894-899

##article.numberofdownloads## 51

##article.numberofviews## 131

PDF (Русский)

References

Волченко Н.Н., Борисова О.В. Диагностика злокачественных опухолей по серозным экссудатам / Цитологический атлас. - М., «Гоэтар-Медиа», 2017. - 144 с.

Григорук О.Г., Лазарев А.Ф., Богатырев В.Н. Дифференциальная цитологическая диагностика плевритов / Монография - Барнаул: Алтайский филиал ФГБУ РОНЦ им. Н.Н. Блохина, 2012. - 258 с.

Иванов О.В., Клименко В.Н., Новик В.И., Николаев Г.В. Иммуноцитохимия - метод выбора в дифференциальной диагностике опухолевых плевритов неясной этиологии // Ученые записки СПбГМУ им. акад. И.П. Павлова. - 2016. - Т. XXIII. - № 2. - С. 42-46.

Клименко В.Н., Иванов О.В. Диагностика и тактика лечения опухолевых плевритов в амбулаторных условиях // Вопр. онкол. - 2015. - Т. 61. - № 6. - С. 949-955.

Переводчикова Н.И., Алексеева Т.Р Опухолевые плевриты: диагностика и выбор терапевтической тактики // Международный медицинский журнал. - 2003. - № 4. - С. 88-93.

Ganjei-Azar P., Jorda M., Krishan A. Effusion Cytology / A Practical Guide to Cancer Diagnosis. - Demos Medical Publishing, New York, 2011. - 177 p.

Shidham V.B., Atkinson B.F. Cytopathologic diagnosis of serous fluids / 1st ed., Saunders Elsivier, 2007. - 288 p.

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Most read articles by the same author(s)

Andrey Arsenev, Sergey Novikov, Aleksey Barchuk, Sergey Kanaev, Anton Barchuk, S. Tarkov, Andrey Nefedov, K. Kostitsyn, K. Gagua, A. Nefedova, Nikolay Aristidov, LUNG CANCER DIAGNOSIS: NON-INVASIVE AND INVASIVE METHODS , Voprosy onkologii : Vol. 66 No. 1 (2020)
Viktor Novik, D. Dreval, CYTOLOGICAL DIAGNOSIS AS A METHOD OF SCREENING OF PRE-MALIGNANT MELANOCYTIC TUMORS AND EARLY FORMS OF SKIN MELANOMA , Voprosy onkologii : Vol. 64 No. 3 (2018)
Vladimir Bespalov, Aleksey Belyaev, Denis Baranenko, Nikita Khromov-borisov, Valeriy Aleksandrov, Larisa Krasilnikova, Galina Kireeva, Olesya Belyaeva, Konstantin Senchik, Aleksandr Stukov, Irina Vasileva, Aleksandr Semenov, Grigoriy Tochilnikov, Ivan Alvovskiy, Ye. Vyshinskaya, HARMONIZED STATISTICAL ANALYSIS OF THE EFFICACY OF INTRAPERITONEAL CHEMOTHERAPY REGIMENS WITH DIOXADET ON ASCITIC OVARIAN CANCER MODEL , Voprosy onkologii : Vol. 63 No. 2 (2017)
A. Arseniev, A. Nefedova, A. Ganeeva, A. Nefedov, S. Novikov, Anton Barchuk, S. Kanaev, I. Jahatspanian, A. Gubal, A. Kononov, S. Tarkov, N. Aristidov, COMBINED DIAGNOSTICS OF LUNG CANCER USING EXHALED BREATH ANALSYSIS AND SPUTUM CYTOLOGY , Voprosy onkologii : Vol. 66 No. 4 (2020)
Anton Barchuk, A. Atroshchenko, V. Gaydukov, P. Vinogradov, Sergey Tarakanov, Sergey Kanaev, Andrey Arsenev, Yuriy Komarov, Mikhail Kharitonov, Aleksey Barchuk, Vakhtang Merabishvili, Vladimir Kuznetsov, Vladimir Trofimov, Nataliya Gusarova, Igor Kotsyuba, Aleksey Belyaev, Maksim Podolskiy, A. Nefedova, AUTOMATED DIAGNOSIS IN A POPULATION-BASED SCREENING FOR LUNG CANCER , Voprosy onkologii : Vol. 63 No. 2 (2017)
Anton Barchuk, K. Gagua, S. Tarkov, A. Nefedova, Andrey Nefedov, Aleksandr Shcherbakov, Aleksey Barchuk, Sergey Kanaev, Viktor Gombolevskiy, Aleksey Belyaev, Andrey Arsenev, K. Kostitsyn, THE EFFECTIVENESS OF SCREENING FOR CANCER , Voprosy onkologii : Vol. 63 No. 4 (2017)
Andrey Arsenev, A. Zagryadskikh, V. Gelfond, K. Gagua, K. Kostitsyn, S. Tarkov, Sergey Kanaev, Anton Barchuk, Andrey Nefedov, A. Nefedova, SINGLE-PORT VIDEO-ASSISTED THORACOSCOPIC LOBECTOMIES IN SURGICAL TREATMENT FOR LUNG CANCER , Voprosy onkologii : Vol. 63 No. 3 (2017)
Viktor Novik , Development of Clinical Cytology at the N.N. Petrov NMRC of Oncology , Voprosy onkologii : Vol. 69 No. 4 (2023)
Anton Barchuk, V. Satikov, V. Gaydukov, Antonina Chernaya, Sergey Kanaev, Sergey Tarakanov, Yuriy Komarov, Vladimir Kuznetsov, Andrey Arsenev, Aleksey Belyaev, A. Nefedova, THE USE OF ONTOLOGY IN SCREENING FOR CANCER , Voprosy onkologii : Vol. 63 No. 2 (2017)
Andrey Mikhetko, Olga Ivko, Sergey Petrik, O. Tkachenko, M. Grinkevich, A. Sidorova, Yu. Petrik, Yekaterina Shalina, Andrey Mikhetko, OPPORTUNITIES IN DIAGNOSTICS OF PANCREATIC METASTATIC TUMORS BY CYTOLOGICAL METHOD , Voprosy onkologii : Vol. 65 No. 3 (2019)

1 2 > >>