CYTOLOGICAL AND IMMUNOCYTOCHEMICAL DIAGNOSIS OF TUMOR PLEURITIS

ORIGINAL ARTICLES. A. PROTOCOLS OF CLINICAL RESEARCH

https://doi.org/10.37469/0507-3758-2017-63-6-894-899

Published 01.06.2017

Viktor Novik⁺⁻
A. Nefedova⁺⁻
Ye. Yakubo⁺⁻
O. Ivanov⁺⁻
Yekaterina Shalina⁺⁻
Anna Vladimirova⁺⁻
Alla Mikhetko⁺⁻
Larisa Krasilnikova⁺⁻
Viktor Klimenko⁺⁻
T. Lindeberg⁺⁻

Viktor Novik

N.N. Petrov National Medical Research Center of Oncology

A. Nefedova

N.N. Petrov National Medical Research Center of Oncology

Ye. Yakubo

N.N. Petrov National Medical Research Center of Oncology

O. Ivanov

N.N. Petrov National Medical Research Center of Oncology

Yekaterina Shalina

N.N. Petrov National Medical Research Center of Oncology

Anna Vladimirova

N.N. Petrov National Medical Research Center of Oncology

Alla Mikhetko

N.N. Petrov National Medical Research Center of Oncology

Larisa Krasilnikova

N.N. Petrov National Medical Research Center of Oncology

Viktor Klimenko

N.N. Petrov National Medical Research Center of Oncology

T. Lindeberg

N.N. Petrov National Medical Research Center of Oncology

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Keywords

TUMOR PLEURITIS
CYTOLOGICAL DIAGNOSIS
IMMUNOCYTOCHEMICAL STUDY

How to Cite

Novik, V., Nefedova, A., Yakubo, Y., Ivanov, O., Shalina, Y., Vladimirova, A., Mikhetko, A., Krasilnikova, L., Klimenko, V., & Lindeberg, T. (2017). CYTOLOGICAL AND IMMUNOCYTOCHEMICAL DIAGNOSIS OF TUMOR PLEURITIS. Voprosy Onkologii, 63(6), 894–899. https://doi.org/10.37469/0507-3758-2017-63-6-894-899

Abstract

Cytological examination of smears from the sediment after centrifugation of pleural fluids was performed in 479 patients who underwent examination and treatment at our institution in 2014-2016. In 249 (52%) patients tumor cells were not detected in smears, in 230 (48%) observations a suspicion (28 observations) or a confident conclusion (202 observations) on the presence of malignant tumor cells in the exudates was cytologically expressed. In 38 cases immunocytochemical studies was additionally performed. In two observations a false-negative conclusion about the absence of tumor cells in smears was expressed. The sensitivity of the cytological study in the diagnosis of malignant pleuritis was 99.0%. Affirmative cytological conclusions on the presence of malignant pleuritis were given in 87.0% of observations, suspicious cytological responses - in 12.0% of cases. Immunocytochemical studies significantly expanded the possibilities of cytological research and were of great importance in the diagnosis of metastases of tumors of unknown primary localization.

https://doi.org/10.37469/0507-3758-2017-63-6-894-899

PDF (Русский)

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