Гарифуллин, А., Пикин, О., Рябов, А., Александров, О., & Агабекян, Г. (2023). Роль монооксида азота в развитии и лечении онкологических заболеваний. VOPROSY ONKOLOGII, 69(4), 623–630. https://doi.org/10.37469/0507-3758-2023-69-4-623-630

摘要

Оксид азота является одной из важнейших сигнальных клеточных молекул как в патологических, так и в физиологических условиях. Установлено, что оксид азота играет роль в процессе развития онкологических заболеваний, в частности рака простаты, рака молочной железы, рака поджелудочной железы и т. д. При низких концентрациях он оказывает стимулирующее действие на опухолевые клетки, при высоких — наоборот. На протяжении длительного периода времени осуществляются попытки использовать данное соединение для лечения различных опухолей, в том числе и в газообразной форме. Поэтому требуется дальнейшее детальное изучение газообразного оксида азота при лечении онкологических заболеваний и рака лёгкого. Для поиска опубликованных исследований по данной тематике использовались следующие базы данных: Pubmed, Web of Science, EMBASE, РИНЦ и Scopus. Поиск производился во временном интервале с даты создания соответствующей базы данных до февраля 2023 г.

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