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Abstract
This non-systematic review includes studies that present modern ideas about the feasibility, safety, and effectiveness of stereotactic radiation therapy in patients with primary and metastatic spinal tumor lesions, considering the nature and extent of the process and functional status. Local control after the initial treatment of patients is more than 80% in the 12-month follow. For postoperative stereotactic irradiation, the local control is 85-89%. With salvage therapy, it is 66-92%, and as an alternative to surgical decompression 80-84%, with radioresistant metastases 83-85%. The analgesic effect reaches 65-79% with salvage therapy and 92-100% in other cases. Stereotactic radiation therapy can be used in 1 fraction of 16-24Gy or 2-3-5 fractions of 20-25-30Gy. Among the most significant complications of the method are compression fractures of vertebral bodies (11-39%) and myelopathy (1-5%). Careful selection of patients and modern planning techniques play a crucial role in successful treatment. The possibility of stereotactic radiation therapy in patients who have previously been irradiated is a clear advantage for this new option. The method significantly expands the range of specialized care for cancer patients, increases life expectancy, and improves its quality. The research involving various fractionation modes doses fraction is still ongoing. The technique requires high qualifications and sufficient experience from medical personnel and full-fledged diagnostic and radiotherapy equipment. Modern oncology approaches require optimized management of spine tumors, and many aspects of stereotactic radiation therapy remain unresolved and require further research.
References
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