Ключевые слова
Как цитировать
Аннотация
Актуальность. Морфология клеток остается важнейшей областью исследования с момента изобретения микроскопа, получив значительный импульс к развитию с внедрением ультрамикроскопических методов. В данной работе представлен анализ 100 наиболее цитируемых публикаций по морфологии клеток, выполненный с целью определения ключевых тенденций в исследованиях за последние три десятилетия и выявления наиболее значимых работ в данной области.
Материал и методы. Библиометрический анализ выполнен с использованием базы данных Web of Science Core Collection, в которую включены статьи, опубликованные в период с января 1985 г. по апрель 2023 г. Из первоначальной выборки, состоявшей из 1 251 024 публикаций, были отобраны 100 наиболее цитируемых статей. Были извлечены следующие данные: год публикации, количество цитирований, журналы, авторы, географическое распределение, учреждения и ключевые слова. Для статистического анализа и визуализации данных применялись программы VOSviewer и Bibliometrix.
Результаты. Сто наиболее цитируемых статей были опубликованы в 43 журналах, включая издания с высоким импакт-фактором, такие как Nature, Science и Cell. Наиболее цитируемая работа, «Matrix Elasticity Directs Stem Cell Lineage Specification», получила 9 832 цитирования. Авторы из США внесли вклад в размере 70 статей. Ключевыми темами исследований стали изучение механических свойств микроокружения, исследования стволовых клеток и передовые методы визуализации.
Выводы. Настоящее исследование подчёркивает ключевую роль внеклеточного матрикса и сигнальных путей в определении морфологии клеток. Работа также демонстрирует доминирующую роль журналов с высоким импакт-фактором в данной области и указывает на необходимость применения междисциплинарных подходов в будущих исследованиях клеточной морфологии.
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