RESULTS OF TREATMENT OF LOCALLY RECURRING SOFT TISSUES SARCOMAS OF EXTREMITIES

ORIGINAL ARTICLES. A. PROTOCOLS OF CLINICAL RESEARCH

https://doi.org/10.37469/0507-3758-2018-64-3-408-413

Published 01.03.2018

Grigoriy Zinovev⁺⁻
Georgiy Gafton⁺⁻
Sergey Novikov⁺⁻
Ivan Gafton⁺⁻
Yekaterina Busko⁺⁻
Roman Kadyrleev⁺⁻
I. Grinenko⁺⁻
A. Elmurzaev⁺⁻

Grigoriy Zinovev

N.N. Petrov National Medical Research Center of Oncology

Georgiy Gafton

N.N. Petrov National Medical Research Center of Oncology

Sergey Novikov

N.N. Petrov National Medical Research Center of Oncology

Ivan Gafton

N.N. Petrov National Medical Research Center of Oncology

Yekaterina Busko

N.N. Petrov National Medical Research Center of Oncology

Roman Kadyrleev

N.N. Petrov National Medical Research Center of Oncology

I. Grinenko

N.N. Petrov National Medical Research Center of Oncology

A. Elmurzaev

N.N. Petrov National Medical Research Center of Oncology

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Keywords

SOFT TISSUE SARCOMAS
RADIATION THERAPY FOR SARCOMA
SURGICAL TREATMENT FOR SARCOMA
PROGNOSTIC FACTORS
SARCOMA RECURRENCE
RECURRENCE FACTORS

How to Cite

Zinovev, G., Gafton, G., Novikov, S., Gafton, I., Busko, Y., Kadyrleev, R., Grinenko, I., & Elmurzaev, A. (2018). RESULTS OF TREATMENT OF LOCALLY RECURRING SOFT TISSUES SARCOMAS OF EXTREMITIES. Voprosy Onkologii, 64(3), 408–413. https://doi.org/10.37469/0507-3758-2018-64-3-408-413

Abstract

Background: The most striking clinical feature of soft tissues sarcomas (STS) is their ability to recur. At present disputes about the clinical and morphological factors of STS recurrence such as the degree of malignancy, size, location, depth of tumor location, patient’s age and the presence of previous relapses in the anamnesis do not subside. It also requires clarification of the effect of the volume of tissues removed on the long-term results of treatment of STS as well as indications for the application of various regimes of remote radiation therapy.

Materials and methods: Of 1802 registered cases of STS of extremities at the N.N. Petrov National Medical Research Center of Oncology from 2004 to 2016 there were selected data on 213 patients who suffered from at least one relapse of the disease. There was performed an assessment of overall, non-metastatic and disease-free survival using a single-factor (the Kaplan-Meier method) and multivariate analysis (the Cox regression model).

Conclusion: The detection of various prognostic factors of locally recurrent STS allows determining the necessary treatment tactics (the vastness and traumatism of surgery and the advisability of radiation therapy).

https://doi.org/10.37469/0507-3758-2018-64-3-408-413

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##article.numberofviews## 313

PDF (Русский)

References

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