Abstract
The survey of literature includes period from the first attempts of palliative cryodestruction to modern miniinvasive technologies with the use of different methods of navigation and control. Material, that shows scientific validity, efficiency, positive technologic and clinical evolution of method, is collected sufficiently. But despite of general positive and optimistic assessment of cryogenic technologies’ opportunity, there are no results of randomized studies comparing distant results of cryogenic and existing standard treatment of breast cancer. In conclusion authors indicate the objective difficulties in problem’s studying and offer possible resolutions.References
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