Surgical approach with vascular reconstruction after an objective response to neoadjuvant therapy with an EGFR tyrosine kinase inhibitor: clinical case.

CLINICAL CASES

https://doi.org/10.37469/0507-3758-2021-67-2-278-281

Published 06.05.2022

Evgeny Levchenko⁺⁻
Evgeny Slugin⁺⁻
Olga Lopushanskaya⁺⁻
Nikita Levchenko⁺⁻
Fedor Moiseenko⁺⁻
Evgeny Imyanitov⁺⁻
Nikolay Khandogin⁺⁻

Evgeny Levchenko

N.N. Petrov National Medical Research Center of Oncology

Evgeny Slugin

N.N. Petrov National Medical Research Center of Oncology

Olga Lopushanskaya

N.N. Petrov National Medical Research Center of Oncology

Nikita Levchenko

N.N. Petrov National Medical Research Center of Oncology

Fedor Moiseenko

Saint-Petersburg Clinical Scientificand Practical Center for Special Types of Medical Care (oncology-oriented)

Evgeny Imyanitov

N.N. Petrov National Medical Research Center of Oncology

Nikolay Khandogin

N.N. Petrov National Medical Research Center of Oncology

pdf (Русский)

Keywords

lung cancer
EGFR TKI
EGFR mutation
surgical treatment
targeted therapy

How to Cite

Levchenko, E., Slugin, E., Lopushanskaya, O., Levchenko, N., Moiseenko, F., Imyanitov, E., & Khandogin, N. (2022). Surgical approach with vascular reconstruction after an objective response to neoadjuvant therapy with an EGFR tyrosine kinase inhibitor: clinical case. Voprosy Onkologii, 67(2), 278–281. https://doi.org/10.37469/0507-3758-2021-67-2-278-281

Abstract

Tyrosine kinase inhibitors (TKIs) in the neoadjuvant mode and reconstructive techniques in surgical practice may expand the indications for the surgery in the treatment of patients with locally advanced non-small cell lung cancer (NSCLC) containing EGFR mutations.

https://doi.org/10.37469/0507-3758-2021-67-2-278-281

pdf (Русский)

References

Hishida T., Yoshida J., Aokage K. et al. Long-term outcome of surgical resection for residual or regrown advanced non-small cell lung carcinomas following EGFR-TKI treatment: report of four cases. Gen Thorac Cardiovasc Surg. 2016;7:429–33.

Levchenko E. et al. Down-Staging of EGFR Mutation-Positive Advanced Lung Carcinoma with Gefitinib Followed by Surgical Intervention: Follow-Up of Two Cases. Onkologie 2009;32:674–677.

Gomez D.R., Blumenschein G.R. Jr, Lee J.J. et al. Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung.

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