Vol. 68 No. 3 (2022), ORIGINAL ARTICLES. C. CLINICAL RESEARCH

Vol. 68 No. 3 (2022)

SPECT-CT topography of sentinel lymph nodes for radiotherapy of breast cancer

ORIGINAL ARTICLES. C. CLINICAL RESEARCH

https://doi.org/10.37469/0507-3758-2022-68-3-313-321

Published 06.07.2022

Alina Valitova
Iuliia Melnik
Sergei Novikov
Pavel Krzhivitskii
Petr Krivorotko
Zhanna Bryantseva
Irina Akulova
Antonina Chernaya
Nadezhda Popova
Vsevolod Danilov
Sergei Kanaev

Alina Valitova

Iuliia Melnik

Sergei Novikov

Pavel Krzhivitskii

Petr Krivorotko

Zhanna Bryantseva

Irina Akulova

Antonina Chernaya

Nadezhda Popova

Vsevolod Danilov

Sergei Kanaev

##article.numberofdownloads## 147

##article.numberofviews## 180

pdf (Русский)

Keywords

lymph nodes
breast cancer
radiotherapy

How to Cite

Valitova, A., Melnik, I. ., Novikov, S. ., Krzhivitskii, P., Krivorotko, P., Bryantseva, Z. ., Akulova, I., Chernaya, A., Popova, N., Danilov, V., & Kanaev, S. (2022). SPECT-CT topography of sentinel lymph nodes for radiotherapy of breast cancer. Voprosy Onkologii, 68(3), 313–321. https://doi.org/10.37469/0507-3758-2022-68-3-313-321

Abstract

Purpose. To evaluate SPECT-CT topography of sentinel lymph nodes (SLNs) in patients with breast cancer and determine the role of this information for radiotherapy planning.

SPECT-CT was performed in 268 patients with breast cancer. Date acquisition started 1-1,5 hours after intra- and/or peritumoral injection of 150 MBq of ^99mTc-radiocolloids. Finally, we compared topography of visualized SLNs with standard clinical volume designed for irradiation of regional lymph nodes.

SPECT-CT visualized 572 SLNs. In most cases (72,4%) SPECT-CT detected 1-2 SLNs, in 27,6% cases SPECT-CT visualized 3 and more LNs with radiocolloid uptake. Despite high variability of SLNs topography, most of them were localized in the axilla region corresponded to axillary level I-II. Surprisingly, 14,9% LNs were detected in the lateral group of axillary LNs, which are usually not covered by standard LNs contours and often spared during LN dissection.

SPECT-CT visualization of SLNs can be important for individual planning of surgical and radiotherapy treatment.

https://doi.org/10.37469/0507-3758-2022-68-3-313-321

##article.numberofdownloads## 147

##article.numberofviews## 180

pdf (Русский)

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