MOLECULAR DIAGNOSTICS OF BILATERAL BREAST CANCER

ORIGINAL ARTICLES. A. PROTOCOLS OF CLINICAL RESEARCH

https://doi.org/10.37469/0507-3758-2017-63-3-435-439

Published 01.03.2017

Svetlana Bekhtereva⁺⁻
Yevgeniy Imyanitov⁺⁻
Andrey Vazhenin⁺⁻
Alla Domozhirova⁺⁻
Sergey Yaytsev⁺⁻

Svetlana Bekhtereva

Chelyabinsk Regional Clinical Oncology Center, South Ural State Medical University

Yevgeniy Imyanitov

N.N. Petrov Research Institute of Oncology, I.I. Mechnikov North-West State Medical University

Andrey Vazhenin

Chelyabinsk Regional Clinical Oncology Center, South Ural State Medical University

Alla Domozhirova

Chelyabinsk Regional Clinical Oncology Center, South Ural State Medical University

Sergey Yaytsev

Chelyabinsk Regional Clinical Oncology Center, South Ural State Medical University

PDF (Русский)

Keywords

PRIMARY-MULTIPLE MALIGNANT TUMORS
BILATERAL BREAST CANCER
GENETIC STUDIES
RECESSIVE
PREVENTION

How to Cite

Bekhtereva, S., Imyanitov, Y., Vazhenin, A., Domozhirova, A., & Yaytsev, S. (2017). MOLECULAR DIAGNOSTICS OF BILATERAL BREAST CANCER. Voprosy Onkologii, 63(3), 435–439. https://doi.org/10.37469/0507-3758-2017-63-3-435-439

Abstract

The problem of primary multiplicity of malignant tumors remains actual in oncology due to growing number of patients with polyneoplasia especially of the breast. Modern genetic studies use “genetically enriched” cases of cancer, which include in particular primary-multiple malignant tumors of the breast. Practically every tumor has an individual set of somatic mutations and genetic mechanisms of breast cancer appearance are very different. The multicentre study shows the role of recessive determinants of the predisposition to bilateral breast cancer without a family history. The obtained data could be used in clinical practice as a secondary prevention of breast cancer.

https://doi.org/10.37469/0507-3758-2017-63-3-435-439

PDF (Русский)

References

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