Vol. 63 No. 5 (2017), ORIGINAL ARTICLES. A. PROTOCOLS OF CLINICAL RESEARCH

Vol. 63 No. 5 (2017)

LIQUID BIOPSY INDEXES AS PREDICTIVE MARKERS OF CHEMORADIOTHERAPY EFFICACY IN PATIENTS WITH PANCREATIC CANCER

ORIGINAL ARTICLES. A. PROTOCOLS OF CLINICAL RESEARCH

https://doi.org/10.37469/0507-3758-2017-63-5-738-742

Published 01.05.2017

Sergey Ivanov⁺⁻
Luiza Korytova⁺⁻
Igor Ovchinnikov⁺⁻
Ye. Vlasova⁺⁻

Sergey Ivanov

A.M. Granov Russian Research Centre for Radiology and Surgical Technologies

Luiza Korytova

A.M. Granov Russian Research Centre for Radiology and Surgical Technologies

Igor Ovchinnikov

A.M. Granov Russian Research Centre for Radiology and Surgical Technologies

Ye. Vlasova

A.M. Granov Russian Research Centre for Radiology and Surgical Technologies

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Keywords

PANCREATIC CANCER
CHEMORADIOTHERAPY
BLOOD DNA RADIOSENSITIVITY
EFFICACY TREATMENT PREDICTION

How to Cite

Ivanov, S., Korytova, L., Ovchinnikov, I., & Vlasova, Y. (2017). LIQUID BIOPSY INDEXES AS PREDICTIVE MARKERS OF CHEMORADIOTHERAPY EFFICACY IN PATIENTS WITH PANCREATIC CANCER. Voprosy Onkologii, 63(5), 738–742. https://doi.org/10.37469/0507-3758-2017-63-5-738-742

Abstract

Patients with stage IV of pancreatic cancer were locally irradiated by 51 Gy total dose (fraction dose was 3 Gy). Gemcytabin, gemsar + carboplatin, or carboplatin + etoposid + 5-fluorouracil were intraarterially administered as chemotherapy preparations. DNA radiosensitivity biomarkers in patient blood were determined before the treatment start. There was revealed interrelation between value of biochemical index and life span patient. The DNA blood radiosensitivity index determinations are enabled to predict personally the results more success treatment in patients with pancreatic cancer after the use of abovementioned regimens of chemoradiotherapy.

https://doi.org/10.37469/0507-3758-2017-63-5-738-742

##article.numberofdownloads## 24

##article.numberofviews## 67

PDF (Русский)

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