SENTINEL LYMPH NODE BIOPSY USING FLUORESCENT LYMPHOGRAPHY IN CT1-4N0M0 BREAST CANCER PATIENTS: HIGH DIAGNOSTIC CAPABILITIES
Vol. 65 No. 2 (2019), ORIGINAL ARTICLES. A. PROTOCOLS OF CLINICAL RESEARCH
Vol. 65 No. 2 (2019)

SENTINEL LYMPH NODE BIOPSY USING FLUORESCENT LYMPHOGRAPHY IN CT1-4N0M0 BREAST CANCER PATIENTS: HIGH DIAGNOSTIC CAPABILITIES

ORIGINAL ARTICLES. A. PROTOCOLS OF CLINICAL RESEARCH
https://doi.org/10.37469/0507-3758-2019-65-2-243-249
Published 01.02.2019
Sergey Portnoy
Frau Klinik LLC
A. Kuznetsov
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
N. Shakirova
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
Nikolay Kozlov
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
A. Maslyaev
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
A. Karpov
Frau Klinik LLC
Yelena Kampova-polevaya
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
M. Mistakopulo
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
Yuriy Yegorov
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
Olga Anurova
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
Tatyana Shendrikova
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
A. Gornostaeva
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
D. Khaylenko
N.N. Blokhin Cancer Research Center, subdivision of the Ministry of Healthcare of the Russian Federation
PDF (Русский)

Keywords

BREAST CANCER
SENTINEL LYMPH NODE BIOPSY

How to Cite

Portnoy, S., Kuznetsov, A., Shakirova, N., Kozlov, N., Maslyaev, A., Karpov, A., Kampova-polevaya, Y., Mistakopulo, M., Yegorov, Y., Anurova, O., Shendrikova, T., Gornostaeva, A., & Khaylenko, D. (2019). SENTINEL LYMPH NODE BIOPSY USING FLUORESCENT LYMPHOGRAPHY IN CT1-4N0M0 BREAST CANCER PATIENTS: HIGH DIAGNOSTIC CAPABILITIES. Voprosy Onkologii, 65(2), 243–249. https://doi.org/10.37469/0507-3758-2019-65-2-243-249
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Abstract

Breast cancer cT1-4N0M0 patients usually require a sentinel lymph node biopsy. Sentinel lymph node biopsy with indocyanine green fluorescence detection is a modern technique with a high lymph node detection rate. However, the false-negative rate was not evaluated adequately. Our objective was to determine node detection rate and the false-negative rate. 99 patients with 100 cases of breast cancer cT1-4N0M0 were operated on. The axillary part of an operation consisted of indocyanine green fluorescence-guided SLN biopsy and an axillary lymphadenectomy of levels I-II or I-П-Ш. A signal lymph node was detected in 98 cases (98 %). In 28 (28.6%) cases out of 98, metastases in signal lymph nodes were found. Other than sentinel lymph node had metastatic lesion only in 35.7% in SLN N+ cases. False negative result occurred in 1 case of 28 (3.6%). The application of indocyanine green fluorescence-guided sentinel lymph node biopsy in cN0 breast cancer patients allows for a high signal lymph node detection rate and a low false negative rate.
https://doi.org/10.37469/0507-3758-2019-65-2-243-249
PDF (Русский)

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