ВНУТРИБРЮШНАЯ ХИМИОТЕРАПИЯ - СОВРЕМЕННОЕ ВИДЕНИЕ ПРОБЛЕМЫ
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Ключевые слова

ВНУТРИБРЮШНАЯ ХИМИОТЕРАПИЯ
АЭРОЗОЛЬНАЯ ВНУТРИБРЮШНАЯ ХИМИОТЕРАПИЯ
ГИПЕРТЕРМИЯ
ГИПЕРТЕРМИЧЕСКАЯ ХИМИОПЕРФУЗИЯ
КАРЦИНОМАТОЗ БРЮШИНЫ

Аннотация

В лечении карциноматоза брюшины золотым стандартом является выполнение циторедуктивной операции с последующей внутрибрюшной гипертермической химиоперфузией (HIPEC). Однако и при отсутствии видимого карциноматоза, применение HIPEC в адъювантном режиме может снизить риск развития имплантационного метастазирования заболевания по брюшине. Новая методика аэрозольной внутрибрюшной химиотерапии (PIPAC) позволяет при меньших дозах химиопрепарата и широких возможностях к повторным процедурам уменьшить диссеминацию перитонеальных очагов, что в дальнейшем может позволить провести циторедуктивную операцию и HIPEC. Самостоятельное и комбинированное применение каждого из методов и их режимов остается важным и интересным вопросом для дискуссии.

https://doi.org/10.37469/0507-3758-2017-63-5-708-713
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